In this review we consider the effects of endogenous and pharmacological levels of nitrite
under conditions of hypoxia. In humans, the nitrite anion has long been considered as …

Vertebrate hemoglobin (Hb) and myoglobin (Mb) were among the first proteins whose
structures and sequences were determined over 50 years ago. In the subsequent …

Although the primary function of myoglobin (Mb) has been considered to be cellular oxygen
storage and supply, recent studies have suggested to classify Mb as a multifunctional …

Myoglobin is a well-characterized, cytoplasmic hemoprotein that is expressed primarily in
cardiomyocytes and oxidative skeletal muscle fibers. However, recent studies also suggest …

Myoglobin, a mobile carrier of oxygen, is without a doubt an important player central to the
physiological function of heart and skeletal muscle. Recently, researchers have surmounted …

Background—Survivin inhibits apoptosis and regulates cell division in many organs, but its
function in the heart is unknown. Methods and Results—We show that cardiac-specific …

Mechanical forces are able to activate hypertrophic growth of cardiomyocytes in the
overloaded myocardium. However, the transcriptional profiles triggered by mechanical …

Aim: The unexpected identification of myoglobin (MB) in breast cancer prompted us to
evaluate the clinico‐pathological value of MB, haemoglobin (HB) and cytoglobin (CYGB) in …

The identification of novel physiological regulators that stimulate energy expenditure
through brown adipose tissue (BAT) activity in substrate catalysis is of utmost importance to …

Molecular oxygen possesses a dual nature due to its highly reactive free radical property: it
is capable of oxidizing metabolic substrates to generate cellular energy, but can also serve …