Aim The rapid outbreak of the coronavirus disease 2019 (COVID-19) pandemic posed
challenges across different medical fields, especially reproductive health, and gave rise to …

Primary tumors evolve metabolic mechanisms favoring glycolysis for adenosine
triphosphate (ATP) generation and antioxidant defenses. In contrast, metastatic cells …

Male reproductive function is key to the continuation of species and is under sophisticated
regulation, challenged by various stressors including inflammation. In the …

Aquaporins (AQPs) are transmembrane water channels and some of them are permeable in
addition to water to other small solutes including hydrogen peroxide. The sperm cells of …

Background Sperm quality, including semen volume, sperm count, concentration, and total
and progressive motility (collectively,“semen parameters”), has declined in the recent …

Male factor infertility is widely considered a harbinger for a man's general health. Failure of
reproduction often accompanies other underlying processes, with growing evidence …

Importance Numerous studies have documented the association of self-rated health (SRH)
with chronic diseases. However, few studies have investigated its association with semen …

Germline de novo mutations (DNMs) refer to spontaneous mutations arising during
gametogenesis, resulting in genetic changes within germ cells that are subsequently …

Background Poor sleep quality has been linked to lower semen quality, but it is unclear
whether this result in decreased fertility. To address this question, we retrospectively …

An intense period of human population expansion over the past 250 years is about to cease.
Total fertility rates are falling dramatically all over the world such that highly industrialized …