Annulated Heterocyclic[g]Coumarin Composites: Synthetic Approaches and Bioactive Profiling

N Mazin Zeki, Y Fakri Mustafa - Chemistry & Biodiversity, 2024 - Wiley Online Library
Coumarins, widely abundant natural heterocyclic compounds, are extensively employed in
creating various biologically and pharmacologically potent substances. The hybridization of …

6, 7-Coumarin-Heterocyclic Hybrids: A Comprehensive Review of Their Natural Sources, Synthetic Approaches, and Bioactivity

NM Zeki, YF Mustafa - Journal of Molecular Structure, 2024 - Elsevier
The hybridization of heterocycles presents a key opportunity to craft innovative multicyclic
compounds with enhanced biological activity. Coumarins, being broadly prevalent natural …

Chronic Limb-Threatening Ischemia is a Residual Bleeding Risk Factor among Patients with Lower Extremity Artery Disease

T Tokuda, N Yoshioka, A Koyama… - … of Atherosclerosis and …, 2024 - jstage.jst.go.jp
Aim: Lower-extremity artery disease (LEAD) is a high-risk factor for bleeding. However, the
specific risk factors for bleeding in patients with LEAD remain unclear. We aimed to identify …

Emergency Vascular Repairs in Trauma: Predictors of Poor Prognosis and a Novel Scoring System

A Boyev, G Sutton, H Rosenblad… - Journal of Trauma …, 2023 - journals.lww.com
BACKGROUND Vascular injuries comprise 1-4% of all trauma patients and there are no
widely used risk-stratification tools. We sought to establish predictors of revascularization …

[HTML][HTML] Osteoporosis and vascular calcifications

N Martini, L Streckwall, AD McCarthy - Endocrine Connections, 2023 - ec.bioscientifica.com
In post-menopausal women, aged individuals, and patients with diabetes mellitus or chronic
renal disease, bone mineral density (BMD) decreases while the vasculature accumulates …

[PDF][PDF] Bridging the Gap: Integrating Research Findings into Clinical Practice for Pancreatitis and Cystic Fibrosis Management

N Rita - 2023 - pea.lib.pte.hu
In the past decade, the concept of evidence-based medicine (EBM) has been clearly defined
(1). The advantage of this approach is to avoid deficiencies in clinical care that rely on local …