Impact of childhood malnutrition on host defense and infection

MK Ibrahim, M Zambruni, CL Melby… - Clinical microbiology …, 2017 - Am Soc Microbiol
The global impact of childhood malnutrition is staggering. The synergism between
malnutrition and infection contributes substantially to childhood morbidity and mortality …

Design considerations for liposomal vaccines: influence of formulation parameters on antibody and cell-mediated immune responses to liposome associated antigens

DS Watson, AN Endsley, L Huang - Vaccine, 2012 - Elsevier
Liposomes (phospholipid bilayer vesicles) are versatile and robust delivery systems for
induction of antibody and T lymphocyte responses to associated subunit antigens. In the last …

ESX‐1‐mediated translocation to the cytosol controls virulence of mycobacteria

D Houben, C Demangel, J Van Ingen… - Cellular …, 2012 - Wiley Online Library
Mycobacterium species, including Mycobacterium tuberculosis and Mycobacterium leprae,
are among the most potent human bacterial pathogens. The discovery of cytosolic …

Pathways of polyunsaturated fatty acid utilization: implications for brain function in neuropsychiatric health and disease

JJ Liu, P Green, JJ Mann, SI Rapoport, ME Sublette - Brain research, 2015 - Elsevier
Essential polyunsaturated fatty acids (PUFAs) have profound effects on brain development
and function. Abnormalities of PUFA status have been implicated in neuropsychiatric …

[HTML][HTML] Narrative Review of n-3 Polyunsaturated Fatty Acid Supplementation upon Immune Functions, Resolution Molecules and Lipid Peroxidation

GP Zaloga - Nutrients, 2021 - mdpi.com
Fish oil supplementation is commonplace in human nutrition and is being used in both
enteral and parenteral formulations during the treatment of patients with a large variety of …

Targeting GPR120 and other fatty acid-sensing GPCRs ameliorates insulin resistance and inflammatory diseases

S Talukdar, JM Olefsky, O Osborn - Trends in pharmacological sciences, 2011 - cell.com
The past decade has seen great progress in the understanding of the molecular
pharmacology, physiological function and therapeutic potential of G-protein-coupled …

Biophysical and biochemical mechanisms by which dietary N-3 polyunsaturated fatty acids from fish oil disrupt membrane lipid rafts

SR Shaikh - The Journal of nutritional biochemistry, 2012 - Elsevier
N-3 polyunsaturated fatty acids (PUFAs) from fish oil exert their functional effects by targeting
multiple mechanisms. One mechanism to emerge in the past decade is the ability of n-3 …

Immunomodulation by dietary long chain omega-3 fatty acids and the potential for adverse health outcomes

JI Fenton, NG Hord, S Ghosh, EA Gurzell - … , Leukotrienes and Essential …, 2013 - Elsevier
Recommendations to consume fish for prevention of cardiovascular disease (CVD), along
with the US Food and Drug Administration-approved generally recognized as safe (GRAS) …

[HTML][HTML] Fish oil and inflammatory status alter the n-3 to n-6 balance of the endocannabinoid and oxylipin metabolomes in mouse plasma and tissues

MGJ Balvers, KCM Verhoeckx, S Bijlsma, CM Rubingh… - Metabolomics, 2012 - Springer
It is well established that dietary intake of n-3 fatty acids is associated with anti-inflammatory
effects, and this has been linked to modulation of the oxylipin and endocannabinoid …

Fatty acids-induced lipotoxicity and inflammation

S Savary, D Trompier, P Andréoletti… - Current drug …, 2012 - ingentaconnect.com
Fatty acids are known to serve as energetic substrates, key components of membrane lipids,
and as substrates for the synthesis of signaling molecules and complex lipids. They are also …