Treatments in ischemic stroke: current and future

MG Mosconi, M Paciaroni - European neurology, 2022 - karger.com
Abstract Background and Aim: Despite progress made over the last 30 years, stroke is still a
leading cause of disability and mortality; likewise, its burden is expected to increase over the …

Antiplatelet therapy in cardiovascular disease: Current status and future directions

G Passacquale, P Sharma, D Perera… - British Journal of …, 2022 - Wiley Online Library
Antiplatelet medications remain a cornerstone of therapy for atherosclerotic cardiovascular
and cerebrovascular diseases. In primary prevention (patients with cardiovascular risk …

[HTML][HTML] Aspirin resistance in vascular disease: a review highlighting the critical need for improved point-of-care testing and personalized therapy

H Khan, O Kanny, MH Syed, M Qadura - International journal of molecular …, 2022 - mdpi.com
Aspirin resistance describes a phenomenon where patients receiving aspirin therapy do not
respond favorably to treatment, and is categorized by continued incidence of adverse …

Role of the platelets and nitric oxide biotransformation in ischemic stroke: a translative review from bench to bedside

M Bladowski, J Gawrys, D Gajecki… - Oxidative Medicine …, 2020 - Wiley Online Library
Ischemic stroke remains the fifth cause of death, as reported worldwide annually.
Endothelial dysfunction (ED) manifesting with lower nitric oxide (NO) bioavailability leads to …

Aspirin versus clopidogrel as single antithrombotic therapy after transcatheter aortic valve replacement: insight from the OCEAN-TAVI registry

Y Kobari, T Inohara, T Saito, N Yoshijima… - Circulation …, 2021 - Am Heart Assoc
Background: Current guidelines recommend dual antiplatelet therapy for the first 1 to 6
months after transcatheter aortic valve replacement (TAVR); however, recent studies have …

Acute ischemic stroke management: concepts and controversies. A narrative review

KHC Li, A Jesuthasan, C Kui, R Davies… - Expert Review of …, 2021 - Taylor & Francis
Introduction Amongst the 25.7 million survivors and 6.5 million deaths from stroke between
1990 and 2013, ischemic strokes accounted for approximately 70% and 50% of the cases …

[HTML][HTML] Efficacy and safety of clopidogrel and/or aspirin for ischemic stroke/transient ischemic attack: An overview of systematic reviews and meta-analysis

Y Yang, Z Huang, X Zhang - Medicine, 2021 - journals.lww.com
Objective: Patients experiencing acute ischemic stroke or transient ischemic attack are
commonly treated with clopidogrel and/or aspirin (mono-and dual-antiplatelet therapy) to …

[HTML][HTML] A deep learning-based approach for identifying the medicinal uses of plant-derived natural compounds

S Yoo, HC Yang, S Lee, J Shin, S Min, E Lee… - Frontiers in …, 2020 - frontiersin.org
Medicinal plants and their extracts have been used as important sources for drug discovery.
In particular, plant-derived natural compounds, including phytochemicals, antioxidants …

[HTML][HTML] The impact of preinjury use of antiplatelet drugs on outcomes of traumatic brain injury: a systematic review and meta-analysis

L Cheng, G Cui, R Yang - Frontiers in neurology, 2022 - frontiersin.org
Objective The study aimed to compare outcomes of traumatic brain injury (TBI) in patients on
pre-injury antiplatelet drugs vs. those, not on any antiplatelet or anticoagulant drugs …

[HTML][HTML] Perioperative considerations for antithrombotic therapy in oculofacial surgery: a review of current evidence and practice guidelines

C Kim, ML Pfeiffer, JR Chang… - Ophthalmic Plastic & …, 2022 - journals.lww.com
Purpose: Recent survey studies have demonstrated wide variability in practice patterns
regarding the management of antithrombotic medications in oculofacial plastic surgery …