An artificial intelligence algorithm for co‐clustering to help in pharmacovigilance before and during the COVID‐19 pandemic

A Destere, G Marchello, D Merino… - British Journal of …, 2024 - Wiley Online Library
Aims Monitoring drug safety in real‐world settings is the primary aim of pharmacovigilance.
Frequent adverse drug reactions (ADRs) are usually identified during drug development …

Personalized Approaches to Antiplatelet Treatment for Cardiovascular Diseases: An Umbrella Review

A Oliva, D Cao, A Spirito, J Nicolas… - Pharmacogenomics …, 2023 - Taylor & Francis
Antiplatelet therapy is the cornerstone of antithrombotic prevention in patients with
established atherosclerosis, since it has been proven to reduce coronary, cerebrovascular …

Thrombotic events associated with immune checkpoint inhibitors and novel antithrombotic strategies to mitigate bleeding risk

J Chen, S Liu, Z Ruan, K Wang, X Xi, J Mao - Blood Reviews, 2024 - Elsevier
Although immunotherapy is expanding treatment options for cancer patients, the prognosis
of advanced cancer remains poor, and these patients must contend with both cancers and …

[HTML][HTML] Platelet morphology, ultrastructure and function changes in acute ischemic stroke patients based on structured illumination microscopy

B Yang, X Wang, X Hu, Y Xiao, X Xu, X Yu, M Wang… - Heliyon, 2023 - Elsevier
Acute ischemic stroke (AIS) is the second leading cause of death worldwide. This study aims
at assessing platelet morphology, ultrastructure and function changes of platelets in acute …

Clinical and genetic heterogeneity in a large family with pseudoxanthoma elasticum: MTHFR and SERPINE1 variants as possible disease modifiers in developing …

G Bruno, M Ritelli, A Di Pietro, L Cipriano… - Journal of Stroke and …, 2021 - Elsevier
Background and objectives Pseudoxanthoma elasticum (PXE) is a rare autosomal recessive
disorder caused by pathogenic variants in the ABCC6 gene. The phenotypic spectrum of …

Use of ticagrelor and the risks of pneumonia and pneumonia-specific death in patients with non-acute coronary syndrome conditions: a population-based cohort study

Q Feng, MF Tsoi, Y Fei, CL Cheung, BMY Cheung - Scientific Reports, 2021 - nature.com
Previous studies have shown that ticagrelor reduced risk of pneumonia in patients with
acute coronary syndrome (ACS) compared to clopidogrel, however, its effect in patients with …

Long-term effectiveness and safety of cilostazol versus clopidogrel in secondary prevention of noncardioembolic ischemic stroke

YJ Lee, NK Je - European Journal of Clinical Pharmacology, 2023 - Springer
Purpose Cilostazol is a widely used antiplatelet drug for secondary stroke prevention in
Asia, but its comparison with clopidogrel is not well understood. This study aims to …

Ethnic and Gender Variations in Ischemic Stroke Patterns among Arab Populations in Northern Israel: A Preliminary Exploration towards Culturally Aware …

CH Ryder, C Gal, G Barkay, S Raveh Amsalem… - Journal of Personalized …, 2024 - mdpi.com
The Galilee region of Israel boasts a rich ethnic diversity within its Arab population,
encompassing distinct Muslim, Christian, Druze, and Bedouin communities. This preliminary …

[HTML][HTML] The importance of intensive follow-up and achieving optimal chronic antithrombotic treatment in hospitalized medical patients with anemia: A prospective …

A Papazachariou, JA Papadakis, V Malikides… - Hellenic Journal of …, 2024 - Elsevier
Background Anemia is a global health concern, particularly among the elderly on chronic
antithrombotic treatment. Close monitoring of hemoglobin (Hb) levels and achievement of an …

Safety and Efficacy of Baseline Antiplatelet Treatment in Patients Undergoing Mechanical Thrombectomy for Ischemic Stroke: Antiplatelets Before Mechanical …

T Klail, P Sedova, JF Vinklarek, I Kovacova… - Journal of Vascular and …, 2023 - Elsevier
Purpose To investigate the safety and efficacy of baseline antiplatelet treatment in patients
with acute ischemic stroke (AIS) undergoing mechanical thrombectomy (MT). Materials and …