The biosynthesis of the zinc finger transcription factor Egr‐1 is stimulated by many
extracellular signaling molecules including hormones, neurotransmitters, growth and …

Hepatocellular carcinoma (HCC) is the second leading cause of cancer-related deaths
worldwide. There are two major challenges for HCC, the first being that early detection is …

In the mammary gland, the stromal extracellular matrix (ECM) undergoes dramatic changes
during development and in tumorigenesis. For example, normal adult breast tissue is largely …

Hepatocyte growth factor/scatter factor (HGF) exerts several functions in physiological and
pathological processes, among them the induction of epithelial cell scattering and motility. Its …

The tricarboxylic acid (TCA) cycle converts the end products of glycolysis and fatty acid β-
oxidation into the reducing equivalents NADH and FADH2. Although mitochondrial matrix …

Troglitazone (TGZ) is a peroxisome proliferator-activated receptor γ (PPARγ) ligand that has
pro-apoptotic activity in human colon cancer. Although TGZ binds to PPARγ transcription …

Natural luteolysis involves multiple pulses of prostaglandin F2alpha (PGF) released by the
nonpregnant uterus. This study investigated expression of 18 genes from five distinct …

The hormone insulin executes its function via binding and activating of the insulin receptor, a
receptor tyrosine kinase that is mainly expressed in skeletal muscle, adipocytes, liver …

The epidermal growth factor (EGF) receptor is highly expressed in HaCaT keratinocytes as
shown by Western blotting. Stimulation of HaCaT cells with EGF, and also with the serine …

Signalling via the p42/44 mitogen‐activated protein kinase (MAPK) pathway has been
identified as an intermediate event coupling light to entrainment of the mammalian circadian …