[图书][B] Human behavior in the social environment: Perspectives on development, the life course, and macro contexts
A Rogers - 2020 - taylorfrancis.com
In this new aggregated edition of Anissa Taun Roger's Human Behavior in the Social
Environment, readers will find a comprehensive overview of the issues related to human …
Environment, readers will find a comprehensive overview of the issues related to human …
[HTML][HTML] Mutations and Modeling of the Chromatin Remodeler CHD8 Define an Emerging Autism Etiology
RA Barnard, MB Pomaville, BJ O'roak - Frontiers in neuroscience, 2015 - frontiersin.org
Autism Spectrum Disorder (ASD) is a common neurodevelopmental disorder with a strong
but complex genetic component. Recent family based exome-sequencing strategies have …
but complex genetic component. Recent family based exome-sequencing strategies have …
[HTML][HTML] Regulatory domain or CpG site variation in SLC12A5, encoding the chloride transporter KCC2, in human autism and schizophrenia
ND Merner, MR Chandler, C Bourassa… - Frontiers in cellular …, 2015 - frontiersin.org
Many encoded gene products responsible for neurodevelopmental disorders (NDs) like
autism spectrum disorders (ASD), schizophrenia (SCZ), intellectual disability (ID), and …
autism spectrum disorders (ASD), schizophrenia (SCZ), intellectual disability (ID), and …
[HTML][HTML] MicroRNA profiling of neurons generated using induced pluripotent stem cells derived from patients with schizophrenia and schizoaffective disorder, and …
We are using induced pluripotent stem cell (iPSC) technology to study neuropsychiatric
disorders associated with 22q11. 2 microdeletions (del), the most common known …
disorders associated with 22q11. 2 microdeletions (del), the most common known …
[HTML][HTML] Full-length isoform transcriptome of the developing human brain provides further insights into autism
Alternative splicing plays an important role in brain development, but its global contribution
to human neurodevelopmental diseases (NDDs) requires further investigation. Here we …
to human neurodevelopmental diseases (NDDs) requires further investigation. Here we …
Schizophrenia: susceptibility genes, dendritic-spine pathology and gray matter loss
MR Bennett - Progress in neurobiology, 2011 - Elsevier
Gray matter loss in the cortex is extensive in schizophrenia, especially in the prefrontal-
temporal-network (PTN). Several molecules such as neuregulin-1 (NRG1) and its ErbB4 …
temporal-network (PTN). Several molecules such as neuregulin-1 (NRG1) and its ErbB4 …
The role of genetics and genomics in clinical psychiatry
MR Hoehe, DJ Morris-Rosendahl - Dialogues in clinical …, 2018 - Taylor & Francis
The enormous successes in the genetics and genomics of many diseases have provided the
basis for the advancement of precision medicine. Thus, the detection of genetic variants …
basis for the advancement of precision medicine. Thus, the detection of genetic variants …
[HTML][HTML] Paternal-age-related de novo mutations and risk for five disorders
There are established associations between advanced paternal age and offspring risk for
psychiatric and developmental disorders. These are commonly attributed to genetic …
psychiatric and developmental disorders. These are commonly attributed to genetic …
[HTML][HTML] Pathogenetic model for Tourette syndrome delineates overlap with related neurodevelopmental disorders including Autism
Tourette syndrome (TS) is a highly heritable neuropsychiatric disorder characterised by
motor and vocal tics. Despite decades of research, the aetiology of TS has remained elusive …
motor and vocal tics. Despite decades of research, the aetiology of TS has remained elusive …
[HTML][HTML] Synaptic plasticity, neural circuits, and the emerging role of altered short-term information processing in schizophrenia
GW Crabtree, JA Gogos - Frontiers in synaptic neuroscience, 2014 - frontiersin.org
Synaptic plasticity alters the strength of information flow between presynaptic and
postsynaptic neurons and thus modifies the likelihood that action potentials in a presynaptic …
postsynaptic neurons and thus modifies the likelihood that action potentials in a presynaptic …