Transcriptional regulation in mammalian cells is driven by a complex interplay of multiple
transcription factors that respond to signals from either external or internal stimuli. A single …

Tumor suppressor genes and proto-oncogenes comprise most of the complex genomic
landscape associated with cancer, with a minimal number of genes exhibiting dual-context …

The mammalian genome contains two ERK/MAP kinase kinase genes, Map2k1 and
Map2k2, which encode dual-specificity kinases responsible for ERK activation. Loss of …

The transcription factor LSF (Late SV40 Factor), also known as TFCP2, belongs to the
LSF/CP2 family related to Grainyhead family of proteins and is involved in many biological …

Nuclear phosphoinositides, especially phosphatidylinositol 4, 5-bisphosphate, fluctuate
throughout the cell cycle and are linked to proliferation and differentiation. Here we report …

The mammalian genome contains two ERK/MAP kinase kinase genes, Map2k1 and
Map2k2, which encode dual-specificity kinases responsible for ERK/MAP kinase activation …

Aberrant activation of beta-catenin/TCF (T-cell factor) signaling is frequently observed in the
pancreatic cancer. However, the regulation of nuclear beta-catenin/TCF transcription …

AIM: To investigate the relationship between late SV40 factor (LSF) and Notch signaling in
the development and progress of hepatocellular carcinoma (HCC). METHODS: Liver cancer …

Cell cycle progression in mammalian cells from G1 into S phase requires sensing and
integration of multiple inputs, in order to determine whether to continue to cellular DNA …

Abstract Late SV40 factor 3 (LSF), a transcription factor, contributes to human hepatocellular
carcinoma (HCC). However, decreased expression level of LSF in skin melanoma …