Prussian blue (PB) nanoparticles possess excellent physicochemical properties, including
imaging features, robust photothermal conversion ability, catalytic activity, surface …

Macrophages are one of the first innate immune cells to reach the site of infection or injury.
Diverse functions from the uptake of pathogen or antigen, its killing, and presentation, the …

The pivotal role of the tumor microenvironment (TME) in the initiation and advancement of
hepatocellular carcinoma (HCC) is widely acknowledged, as it fosters the proliferation and …

The “do not eat me” signaling pathway is extremely active in tumor cells, providing a means
for these cells to elude macrophage phagocytosis and escape immune surveillance …

Phospholipase D (PLD) is a potential therapeutic target against cancer. However, the
contribution of PLD inhibition to the antitumor response remains unknown. We developed a …

Exosomes can be released by a variety of cells and participate in intercellular
communication in many physiological processes in the body. They can be used as carriers …

The efficacy of cancer therapies is limited to a great extent by immunosuppressive
mechanisms within the tumor microenvironment (TME). Numerous immune escape …

Immunosuppressive myeloid cell populations have been documented in small cell lung
cancer (SCLC) subtypes, playing a key role in remolding the tumor microenvironment (TME) …

Background RARRES1 is a tumor suppressor protein, and its expression is suppressed in
various tumor cells. However, whether it participates in the immune response in kidney renal …

Immunotherapy with therapeutic antibodies has shown a lack of durable responses in some
patients due to resistance mechanisms. Checkpoint molecules expressed by tumor cells …