There is increasing interest in the origins of chronic obstructive pulmonary disease (COPD),
as it is envisaged that preventive efforts and treatment can modify its clinical course. The …

Chronic obstructive pulmonary disease (COPD) affects one-tenth of the world's population
and has been identified as a major global unmet health need by the World Health …

Here, we present a physiologically relevant model of the human pulmonary alveoli. This
alveolar lung-on-a-chip platform is composed of a three-dimensional porous hydrogel made …

Background Interest in lifetime lung function trajectories has increased in the context of
emerging evidence that chronic obstructive pulmonary disease (COPD) can arise from …

Smoking represents a major risk factor for chronic obstructive pulmonary disease (COPD),
but it is difficult to characterize smoke-induced injury responses under physiological …

Abstract Purpose Coronavirus disease 2019 (COVID-19) is creating an unprecedented
healthcare crisis. Understanding the determinants of mortality is crucial to optimise intensive …

Chronic obstructive pulmonary disease (COPD) is a prevalent, heterogeneous disorder with
varying presentation and progression but with a limited number of disease-modifying …

Rationale: Chronic obstructive pulmonary disease (COPD) is often unrecognized and
untreated. Objectives: To develop a method for identifying undiagnosed COPD requiring …

Chronic obstructive pulmonary disease (COPD) is a disease with high incidence rate and
mortality rates worldwide. It is the third leading cause of death in the world. Nevertheless …

Rationale: Individuals who will develop chronic obstructive pulmonary disease (COPD)
could be identified at an early age before clinical manifestations appear. Objectives: We …