Since the first dendrimer was reported in 1978 by Fritz Vögtle, dendrimer research has
grown exponentially, from synthesis to application in the past four decades. The distinct …

Ocular drug delivery is challenging due to the presence of anatomical and physiological
barriers. These barriers can affect drug entry into the eye following multiple routes of …

Dendrimers are hyper-branched organic compounds characterized via a three-dimensional
structure possessing functional groups on the surface. These terminals groups can be …

A drug's aqueous solubility is defined as the ability to dissolve in a particular solvent, and it
is currently a major hurdle in bringing new drug molecules to the market. According to some …

Polymeric vehicles are versatile tools for therapeutic gene delivery. Many polymers—when
assembled with nucleic acids into vehicles—can protect the cargo from degradation and …

Anatomy and physiology of the eye makes it a highly protected organ. Designing an effective
therapy for ocular diseases, especially for the posterior segment, has been considered as a …

The application of nanotechnology in medicine and pharmaceuticals is a rapidly advancing
field that is quickly gaining acceptance and recognition as an independent area of research …

Written at a level comprehensible to non-experts, this handbook covers the current state of
encapsulation and controlled released technologies, presenting the fundamental processes …

The drug candidates coming from combinatorial chemistry research and/or the drugs
selected from biologically based high-throughput screening are quite often very lipophilic, as …

Despite numerous scientific efforts, efficient ocular drug delivery remains a challenge for
pharmaceutical scientists. Most ocular diseases are treated by topical drug application in the …