Cancer drug delivery systems using bacterial toxin translocation mechanisms

L Yin, H Thaker - Bioengineering, 2023 - mdpi.com
Recent advances in targeted cancer therapy hold great promise for both research and
clinical applications and push the boundaries in finding new treatments for various currently …

Challenges of Diphtheria Toxin Detection

M Prygiel, E Mosiej, M Polak, K Krysztopa-Grzybowska… - Toxins, 2024 - mdpi.com
Diphtheria toxin (DT) is the main virulence factor of Corynebacterium diphtheriae, C.
ulcerans and C. pseudotuberculosis. Moreover, new Corynebacterium species with the …

Corynebacterium ulcerans Infections in Eurasian Beavers (Castor fiber)

R Sting, C Pölzelbauer, T Eisenberg, R Bonke… - Pathogens, 2023 - mdpi.com
The Eurasian beaver (Castor fiber) has been reintroduced successfully in Germany since
the 1990s. Since wildlife is an important source of zoonotic infectious diseases, monitoring …

The DarT/DarG toxin–antitoxin ADP-ribosylation system as a novel target for a rational design of innovative antimicrobial strategies

G Catara, R Caggiano, L Palazzo - Pathogens, 2023 - mdpi.com
The chemical modification of cellular macromolecules by the transfer of ADP-ribose unit (s),
known as ADP-ribosylation, is an ancient homeostatic and stress response control system …

[HTML][HTML] Proteomics of Toxigenic Corynebacteria

A Burkovski - Proteomes, 2024 - mdpi.com
Within the genus Corynebacterium, six species are potential carriers of the tox gene, which
encodes the highly potent diphtheria exotoxin: Corynebacterium diphtheriae …

Skin and Soft Tissue Infections: Current Advancement in Epidemiology, Pathogenesis and Management.

A Goel, N Aggarwal, G Kapoor… - Journal of Pure & …, 2023 - search.ebscohost.com
Skin and soft tissue infections are brought on by invasion of microbes on the skin and
underlying soft tissues (SSTIs). They appear in a series of shapes, causes the high level of …

[HTML][HTML] Corynebacterium pseudotuberculosis biovar ovis Strains Isolated from Small Ruminants Herds from the Brazilian Amazon Present Clonal Genomic Profile

SM do Nascimento Sousa, ACS Lima… - Small Ruminant …, 2024 - Elsevier
This study tested the hypothesis that Corynebacterium pseudotuberulosis strains isolated
from small herds of ruminants in the state of Pará have a clonal genomic profile. Serum …

Molecular characterization and phylogenetic analysis of the first Corynebacterium rouxii strains isolated in Brazil: a recent member of Corynebacterium diphtheriae …

JN Ramos, MRB Araújo, PVP Baio, LO Sant'Anna… - BMC Genomic …, 2023 - Springer
Background Corynebacterium diphtheriae complex was formed by the species C.
diphtheriae, Corynebacterium ulcerans and Corynebacterium pseudotuberculosis in the …

[HTML][HTML] Notes from the Field: Increase in Nontoxigenic Corynebacterium diphtheriae—Washington, 2018–2023

AG Xie - MMWR. Morbidity and Mortality Weekly Report, 2024 - cdc.gov
Corynebacterium diphtheriae infections can be caused by toxigenic and nontoxigenic
strains. Diphtheria toxoid–containing vaccines (DTaP, Tdap, Td) only protect against …

[HTML][HTML] Lateral flow immunoassay-based laboratory algorithm for rapid diagnosis of diphtheria

VG Melnikov, A Berger, A Dangel, A Sing - Open Research Europe, 2023 - ncbi.nlm.nih.gov
Background: In industrialised countries diphtheria is a rare but still life-threatening disease
with a recent increase in cases due to migration and zoonotic aspects. Due to the rarity of …