The natriuretic peptides system in the pathophysiology of heart failure: from molecular basis to treatment

M Volpe, M Carnovali, V Mastromarino - Clinical Science, 2016 - portlandpress.com
After its discovery in the early 1980s, the natriuretic peptide (NP) system has been
extensively characterized and its potential influence in the development and progression of …

Natriuretic peptides in heart failure: atrial and B-type natriuretic peptides

AS Maisel, JM Duran, N Wettersten - Heart failure clinics, 2018 - heartfailure.theclinics.com
The natriuretic peptides (NPs) play a critical role in maintaining homeostasis in the
cardiovascular system, serving as counter-regulatory hormones for volume and pressure …

[HTML][HTML] Natriuretic peptides and cardio-renal disease

M Volpe - International journal of cardiology, 2014 - Elsevier
The natriuretic peptide (NP) system is an important endocrine, autocrine and paracrine
system, consisting of a family of peptides which provide cardiac, renal and vascular effects …

Integrated activity of cardiovascular and pain regulatory systems: role in adaptive behavioural responses

TA Lovick - Progress in neurobiology, 1993 - Elsevier
Responsiveness to sensory stimulation can undergo marked changes during the daily life
cycle. The sleeping or drowsy person may not respond to auditory or tactile stimuli which …

Angiotensin receptor–neprilysin inhibitors for hypertension—hemodynamic effects and relevance to hypertensive heart disease

K Kario, B Williams - Hypertension Research, 2022 - nature.com
Angiotensin receptor–neprilysin inhibitors have multiple beneficial effects on the
cardiovascular system. The angiotensin receptor–neprilysin inhibitor sacubitril/valsartan has …

[HTML][HTML] ARNi: a novel approach to counteract cardiovascular diseases

M Volpe, S Rubattu, A Battistoni - International journal of molecular …, 2019 - mdpi.com
Cardiovascular diseases (CVDs) still represent the greatest burden on healthcare systems
worldwide. Despite the enormous efforts over the last twenty years to limit the spread of …

Urodilatin, a natriuretic factor from kidneys, can modify renal and cardiovascular function in men

H Saxenhofer, A Raselli, P Weidmann… - American Journal …, 1990 - journals.physiology.org
Urodilatin is a newly identified analogue of human atrial natriuretic factor-(99-126)[ANF-(99-
126)], which has recently been isolated from human urine and has 32 amino acid residues …

ANP in regulation of arterial pressure and fluid-electrolyte balance: lessons from genetic mouse models

LG MELO, ME STEINHELPER… - Physiological …, 2000 - journals.physiology.org
Melo, Luis G., Mark E. Steinhelper, Stephen C. Pang, Yat Tse, and Uwe Ackermann. ANP in
the regulation of arterial pressure and fluid-electrolyte balance: lessons from genetic mouse …

Adaptations in autonomic nervous system regulation in normal and hypertensive pregnancy

VL Brooks, Q Fu, Z Shi, CM Heesch - Handbook of Clinical Neurology, 2020 - Elsevier
There is an increase in basal sympathetic nerve activity (SNA) during normal pregnancy; this
counteracts profound primary vasodilation. However, pregnancy also impairs baroreflex …

Natriuretic peptides in heart failure: Current achievements and future perspectives

M Volpe, A Battistoni, S Rubattu - International journal of cardiology, 2019 - Elsevier
The last two centuries have witnessed countless discoveries in the field of medicine that
found their roots in the up growing development of technology as well as in the visionary …