How can we use the endocytosis pathways to design nanoparticle drug-delivery vehicles to target cancer cells over healthy cells?
VT Cong, JL Houng, M Kavallaris, X Chen… - Chemical Society …, 2022 - pubs.rsc.org
Targeted drug delivery in cancer typically focuses on maximising the endocytosis of drugs
into the diseased cells. However, there has been less focus on exploiting the differences in …
into the diseased cells. However, there has been less focus on exploiting the differences in …
Macrophage membrane coated nanoparticles: a biomimetic approach for enhanced and targeted delivery
N Khatoon, Z Zhang, C Zhou, M Chu - Biomaterials science, 2022 - pubs.rsc.org
The enhanced and targeted drug delivery with low systemic toxicity and subsequent release
of drugs is a major concern among researchers and pharmaceutics. In spite of greater …
of drugs is a major concern among researchers and pharmaceutics. In spite of greater …
Harnessing engineered immune cells and bacteria as drug carriers for cancer immunotherapy
Immunotherapy continues to be in the spotlight of oncology therapy research in the past few
years and has been proven to be a promising option to modulate one's innate and adaptive …
years and has been proven to be a promising option to modulate one's innate and adaptive …
Macrophages as promising carriers for nanoparticle delivery in anticancer therapy
A Wróblewska, A Szczygieł… - International Journal …, 2023 - Taylor & Francis
Macrophages play a critical role in the immune response due to their ability to recognize and
remove pathogens, as well as present antigens, which are involved in inflammation, but they …
remove pathogens, as well as present antigens, which are involved in inflammation, but they …
Macrophage In Vitro and In Vivo Tracking via Anchored Microcapsules
AY Sapach, OA Sindeeva, MV Nesterchuk… - … Applied Materials & …, 2022 - ACS Publications
A new promising trend in personalized medicine is the use of autologous cells
(macrophages or stem cells) for cell-based therapy and also as a “Trojan horse” for targeted …
(macrophages or stem cells) for cell-based therapy and also as a “Trojan horse” for targeted …
Circulation time-optimized albumin nanoplatform for quantitative visualization of lung metastasis via targeting of macrophages
The development of molecular imaging probes to identify key cellular changes within lung
metastases may lead to noninvasive detection of metastatic lesions in the lung. In this study …
metastases may lead to noninvasive detection of metastatic lesions in the lung. In this study …
[HTML][HTML] Exploring monocytes-macrophages in immune microenvironment of glioblastoma for the design of novel therapeutic strategies
MD Caverzán, L Beaugé, PM Oliveda… - Brain Sciences, 2023 - mdpi.com
Gliomas are primary malignant brain tumors. These tumors seem to be more and more
frequent, not only because of a true increase in their incidence, but also due to the increase …
frequent, not only because of a true increase in their incidence, but also due to the increase …
A novel wound dressing based on epigallocatechin-3-gallate self-assemble hydrogels promotes effects on wound healing
J Zhu, R Hou, M Liu, L Wang, W Chen, Y Sun… - Materials Today …, 2022 - Elsevier
Abstract Epigallocatechin-3-gallate (EGCG) is an excellent natural product that is beneficial
to wound healing, but the easy oxidation of EGCG limits its wide application. Herein, we …
to wound healing, but the easy oxidation of EGCG limits its wide application. Herein, we …
[HTML][HTML] Macrophage-based microrobots for anticancer therapy: recent progress and future perspectives
Macrophages, which are part of the mononuclear phagocytic system, possess sensory
receptors that enable them to target cancer cells. In addition, they are able to engulf large …
receptors that enable them to target cancer cells. In addition, they are able to engulf large …
Nanomedicine approaches for medulloblastoma therapy
C Lim, J Koo, KT Oh - Journal of Pharmaceutical Investigation, 2023 - Springer
Background Over the past 30 years, brain tumors have been intensively studied with a
variety of therapeutic approaches. However, brain cancer is still one of the most lethal forms …
variety of therapeutic approaches. However, brain cancer is still one of the most lethal forms …