How can we use the endocytosis pathways to design nanoparticle drug-delivery vehicles to target cancer cells over healthy cells?

VT Cong, JL Houng, M Kavallaris, X Chen… - Chemical Society …, 2022 - pubs.rsc.org
Targeted drug delivery in cancer typically focuses on maximising the endocytosis of drugs
into the diseased cells. However, there has been less focus on exploiting the differences in …

Macrophage membrane coated nanoparticles: a biomimetic approach for enhanced and targeted delivery

N Khatoon, Z Zhang, C Zhou, M Chu - Biomaterials science, 2022 - pubs.rsc.org
The enhanced and targeted drug delivery with low systemic toxicity and subsequent release
of drugs is a major concern among researchers and pharmaceutics. In spite of greater …

Harnessing engineered immune cells and bacteria as drug carriers for cancer immunotherapy

J Jiang, Y Huang, Z Zeng, C Zhao - ACS nano, 2023 - ACS Publications
Immunotherapy continues to be in the spotlight of oncology therapy research in the past few
years and has been proven to be a promising option to modulate one's innate and adaptive …

Macrophages as promising carriers for nanoparticle delivery in anticancer therapy

A Wróblewska, A Szczygieł… - International Journal …, 2023 - Taylor & Francis
Macrophages play a critical role in the immune response due to their ability to recognize and
remove pathogens, as well as present antigens, which are involved in inflammation, but they …

Macrophage In Vitro and In Vivo Tracking via Anchored Microcapsules

AY Sapach, OA Sindeeva, MV Nesterchuk… - … Applied Materials & …, 2022 - ACS Publications
A new promising trend in personalized medicine is the use of autologous cells
(macrophages or stem cells) for cell-based therapy and also as a “Trojan horse” for targeted …

Circulation time-optimized albumin nanoplatform for quantitative visualization of lung metastasis via targeting of macrophages

H Chung, JY Park, K Kim, RJ Yoo, M Suh, GJ Gu… - ACS …, 2022 - ACS Publications
The development of molecular imaging probes to identify key cellular changes within lung
metastases may lead to noninvasive detection of metastatic lesions in the lung. In this study …

[HTML][HTML] Exploring monocytes-macrophages in immune microenvironment of glioblastoma for the design of novel therapeutic strategies

MD Caverzán, L Beaugé, PM Oliveda… - Brain Sciences, 2023 - mdpi.com
Gliomas are primary malignant brain tumors. These tumors seem to be more and more
frequent, not only because of a true increase in their incidence, but also due to the increase …

A novel wound dressing based on epigallocatechin-3-gallate self-assemble hydrogels promotes effects on wound healing

J Zhu, R Hou, M Liu, L Wang, W Chen, Y Sun… - Materials Today …, 2022 - Elsevier
Abstract Epigallocatechin-3-gallate (EGCG) is an excellent natural product that is beneficial
to wound healing, but the easy oxidation of EGCG limits its wide application. Herein, we …

[HTML][HTML] Macrophage-based microrobots for anticancer therapy: recent progress and future perspectives

VD Nguyen, JO Park, E Choi - Biomimetics, 2023 - mdpi.com
Macrophages, which are part of the mononuclear phagocytic system, possess sensory
receptors that enable them to target cancer cells. In addition, they are able to engulf large …

Nanomedicine approaches for medulloblastoma therapy

C Lim, J Koo, KT Oh - Journal of Pharmaceutical Investigation, 2023 - Springer
Background Over the past 30 years, brain tumors have been intensively studied with a
variety of therapeutic approaches. However, brain cancer is still one of the most lethal forms …