Frontotemporal lobar degeneration
Frontotemporal lobar degeneration (FTLD) is one of the most common causes of early-onset
dementia and presents with early social–emotional–behavioural and/or language changes …
dementia and presents with early social–emotional–behavioural and/or language changes …
Neurofilament light chain as biomarker for amyotrophic lateral sclerosis and frontotemporal dementia
F Verde, M Otto, V Silani - Frontiers in neuroscience, 2021 - frontiersin.org
Amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD) are two related
currently incurable neurodegenerative diseases. ALS is characterized by degeneration of …
currently incurable neurodegenerative diseases. ALS is characterized by degeneration of …
Comprehensive cross-sectional and longitudinal analyses of plasma neurofilament light across FTD spectrum disorders
TF Gendron, MG Heckman, LJ White, AM Veire… - Cell Reports …, 2022 - cell.com
Frontotemporal dementia (FTD) therapy development is hamstrung by a lack of
susceptibility, diagnostic, and prognostic biomarkers. Blood neurofilament light (NfL) shows …
susceptibility, diagnostic, and prognostic biomarkers. Blood neurofilament light (NfL) shows …
[HTML][HTML] Neuroimaging in frontotemporal dementia: heterogeneity and relationships with underlying neuropathology
Frontotemporal dementia encompasses a group of clinical syndromes defined
pathologically by degeneration of the frontal and temporal lobes. Historically, these …
pathologically by degeneration of the frontal and temporal lobes. Historically, these …
Advances and controversies in frontotemporal dementia: diagnosis, biomarkers, and therapeutic considerations
Frontotemporal dementia comprises a group of clinical syndromes that are characterised by
progressive changes in behaviour, executive function, or language. The term frontotemporal …
progressive changes in behaviour, executive function, or language. The term frontotemporal …
Biomarker discovery and development for frontotemporal dementia and amyotrophic lateral sclerosis
Frontotemporal dementia refers to a group of neurodegenerative disorders characterized by
behaviour and language alterations and focal brain atrophy. Amyotrophic lateral sclerosis is …
behaviour and language alterations and focal brain atrophy. Amyotrophic lateral sclerosis is …
Advances in treatment of frontotemporal dementia
N Magrath Guimet… - The Journal of …, 2022 - Am Neuropsych Assoc
In this review, the authors explored the clinical features of frontotemporal dementia (FTD),
focusing on treatment. The clinical features of FTD are unique, with disinhibition, apathy …
focusing on treatment. The clinical features of FTD are unique, with disinhibition, apathy …
A data-driven disease progression model of fluid biomarkers in genetic frontotemporal dementia
EL Van Der Ende, EE Bron, JM Poos, LC Jiskoot… - Brain, 2022 - academic.oup.com
Several CSF and blood biomarkers for genetic frontotemporal dementia have been
proposed, including those reflecting neuroaxonal loss (neurofilament light chain and …
proposed, including those reflecting neuroaxonal loss (neurofilament light chain and …
From recognition to remedy: The significance of biomarkers in neurodegenerative disease pathology
C Toader, N Dobrin, FM Brehar, C Popa… - International journal of …, 2023 - mdpi.com
With the inexorable aging of the global populace, neurodegenerative diseases (NDs) like
Alzheimer's disease (AD), Parkinson's disease (PD), and amyotrophic lateral sclerosis (ALS) …
Alzheimer's disease (AD), Parkinson's disease (PD), and amyotrophic lateral sclerosis (ALS) …
Distinguishing frontotemporal lobar degeneration tau from TDP-43 using plasma biomarkers
KAQ Cousins, LM Shaw, A Chen-Plotkin… - JAMA …, 2022 - jamanetwork.com
Importance Biomarkers are lacking that can discriminate frontotemporal lobar degeneration
(FTLD) associated with tau (FTLD-tau) or TDP-43 (FTLD-TDP). Objective To test whether …
(FTLD) associated with tau (FTLD-tau) or TDP-43 (FTLD-TDP). Objective To test whether …