Research into the molecular genetics of osteoarthritis (OA) has been substantially bolstered
in the past few years by the implementation of powerful genome-wide scans that have …

Osteoarthritis (OA) is the most common degenerative joint disease that causes painful
swelling and permanent damage to the joints in the body. The molecular mechanisms of OA …

Background Osteoarthritis (OA) is a regular age-related disease that affects millions of
people. Resveratrol (RSV) is a flavonoid with a stilbene structure with different …

Epigenetics of inflammatory arthritis : Current Opinion in Rheumatology Epigenetics of
inflammatory arthritis : Current Opinion in Rheumatology Log in or Register Subscribe to …

DNA methylation has been suggested as a regulatory mechanism behind some
inflammatory processes. The physiological actions of methyl donors, such as folic acid …

The aim of this review is to provide an updated review of the epigenetic factors involved in
the onset and development of osteoarthritis (OA). OA is a prevalent degenerative joint …

Osteoarthritis (OA), a degenerative disease of diarthrodial joints, is influenced by
mechanical and inflammatory factors with aging, obesity, chronic injuries, and secondary …

Aims Previous studies have demonstrated that transcriptional silencing of miRNAs due to
DNA hypermethylation is associated with different pathologies. It has also been reported that …

The ultimate goal of molecular genetic studies of human diseases is to translate the
discoveries for patient benefit. For diseases that lack licensed disease-modifying …

Objective To identify methylation quantitative trait loci (mQTL s) correlating with osteoarthritis
(OA) risk alleles and to undertake mechanistic characterization as a means of target gene …