Ischemia-reperfusion injury (IRI) during renal transplantation often initiates non-specific
inflammatory responses that can result in the loss of kidney graft viability. However, the long …

Background Kidney transplantation is the optimal treatment for end‐stage kidney disease.
Retrieval, transport and transplant of kidney grafts causes ischaemia reperfusion injury. The …

Kidney transplantation is the optimal treatment for end-stage renal disease, but it is still
severely limited by a lack of suitable organ donors. Kidneys from donation after circulatory …

Organs recovered from donors after circulatory death (DCD) suffer warm ischemia before
cold storage which may prejudice graft survival and result in a greater risk of complications …

Organ transplantation is undergoing profound changes. Contraindications for donation have
been revised in order to better meet the organ demand. The use of lower-quality organs and …

Background A program of normothermic ex situ liver perfusion (NESLiP) was developed to
facilitate better assessment and use of marginal livers, while minimizing cold ischemia …

Background A significant proportion of donation after circulatory death (DCD) kidneys are
declined for transplantation because of concerns over their quality. Ex vivo normothermic …

Organ donation after circulatory death (DCD) has been endorsed by the World Health
Organization and is practiced worldwide. This overview examines current DCD practices …

The continuing shortage of deceased donor organs for transplantation, and the limited
number of potential donors after brain death, has led to a resurgence of interest in donation …

Organ transplantation is the most effective therapy for patients with end-stage disease.
Preservation solutions and techniques are crucial for donor organ quality, which is directly …