The monitoring of free flaps, free transplants or organs for transplantation still poses a
problem in medicine. Available systems for the measurement of perfusion and oxygenation …

Summary In 2002, the United Network for Organ Sharing proposed increasing the pool of
donor kidneys to include Expanded Criteria Donor (ECD). Outside the USA, the ECD …

Renal ischemia reperfusion (IR) injury leads to significant patient morbidity and mortality,
and its amelioration is an urgent unmet clinical need. Succinate accumulates during …

Human endothelial cells are initiators and targets of the rejection response. Pre-operative
modification of endothelial cells by small interfering RNA transfection could shape the nature …

We report the successful transplantation of a pair of human kidneys that were declined for
transplantation due to inadequate in situ perfusion but subsequently transplanted after …

Background. The optimal method of oxygen delivery to donor kidneys during ex vivo
machine perfusion has not been established. We have recently reported the beneficial …

Liver transplantation is increasingly dependent on the use of extended criteria donors (ECD)
to increase the organ donor pool and address rising demand. This has necessitated the …

Thousands of kidneys from higher-risk donors are discarded annually because of the
increased likelihood of complications posttransplant. Given the severe organ shortage, there …

ABO blood group compatibility restrictions present the first barrier to donor-recipient
matching in kidney transplantation. Here, we present the use of two enzymes, Fp GalNAc …

Abstract Purpose of Review In this review, we highlight which livers may benefit from
additional treatment before implantation and describe the concept of hypothermic machine …