[HTML][HTML] Ex vivo normothermic perfusion induces donor-derived leukocyte mobilization and removal prior to renal transplantation
JP Stone, AL Ball, WR Critchley, T Major… - Kidney International …, 2016 - Elsevier
Introduction Ex vivo normothermic perfusion offers an alternative method of organ
preservation, allowing donor kidneys to be reanimated and evaluated prior to …
preservation, allowing donor kidneys to be reanimated and evaluated prior to …
[HTML][HTML] Maximizing kidneys for transplantation using machine perfusion: from the past to the future: A comprehensive systematic review and meta-analysis
Background: The two main options for renal allograft preservation are static cold storage
(CS) and machine perfusion (MP). There has been considerably increased interest in MP …
(CS) and machine perfusion (MP). There has been considerably increased interest in MP …
Normothermic machine perfusion systems: where do we go from here?
S López-Martínez, C Simón, X Santamaria - Transplantation, 2024 - journals.lww.com
Normothermic machine perfusion (NMP) aims to preserve organs ex vivo by simulating
physiological conditions such as body temperature. Recent advancements in NMP system …
physiological conditions such as body temperature. Recent advancements in NMP system …
Short, cool, and well oxygenated–HOPE for kidney transplantation in a rodent model
P Kron, A Schlegel, O de Rougemont… - Annals of …, 2016 - journals.lww.com
Objectives: The aim of this study was to investigate novel and easily applicable preservation
perfusion techniques in kidney grafts obtained from donors after circulatory death (DCD) …
perfusion techniques in kidney grafts obtained from donors after circulatory death (DCD) …
[HTML][HTML] Kidney perfusion as an organ quality assessment tool—are we counting our chickens before they have hatched?
J De Beule, I Jochmans - Journal of Clinical Medicine, 2020 - mdpi.com
The final decision to accept an organ for transplantation remains a subjective one. With
“poor organ quality” commonly cited as a major reason for kidney discard, accurate …
“poor organ quality” commonly cited as a major reason for kidney discard, accurate …
Continuous normothermic ex vivo kidney perfusion improves graft function in donation after circulatory death pig kidney transplantation
JM Kaths, J Echeverri, YM Chun, JY Cen… - …, 2017 - journals.lww.com
Background Donation after circulatory death (DCD) is current clinical practice to increase the
donor pool. Deleterious effects on renal graft function are described for hypothermic …
donor pool. Deleterious effects on renal graft function are described for hypothermic …
[HTML][HTML] Synthetic hemoglobin-based oxygen carriers are an acceptable alternative for packed red blood cells in normothermic kidney perfusion
MM Aburawi, FM Fontan, N Karimian, C Eymard… - American Journal of …, 2019 - Elsevier
Normothermic machine perfusion presents a novel platform for pretransplant assessment
and reconditioning of kidney grafts. Maintaining the metabolic activity of a preserved graft at …
and reconditioning of kidney grafts. Maintaining the metabolic activity of a preserved graft at …
Preoperative assessment of the deceased-donor kidney: from macroscopic appearance to molecular biomarkers
AJ Dare, GJ Pettigrew, K Saeb-Parsy - Transplantation, 2014 - journals.lww.com
Variation in deceased-donor kidney quality can significantly affect outcomes after kidney
transplantation. Suboptimal organ selection for a given recipient can result in primary …
transplantation. Suboptimal organ selection for a given recipient can result in primary …
Role of hypothermic machine perfusion in liver transplantation
A Schlegel, P Dutkowski - Transplant International, 2015 - Wiley Online Library
Machine liver perfusion has significantly evolved during the last ten years to optimize
extended criteria liver grafts and to address the worldwide organ shortage. This review gives …
extended criteria liver grafts and to address the worldwide organ shortage. This review gives …
[HTML][HTML] Haemoadsorption reduces the inflammatory response and improves blood flow during ex vivo renal perfusion in an experimental model
SA Hosgood, T Moore, T Kleverlaan, T Adams… - Journal of Translational …, 2017 - Springer
Background Ex-vivo normothermic perfusion strategies are a promising new instrument in
organ transplantation. The perfusion conditions are designed to be protective however the …
organ transplantation. The perfusion conditions are designed to be protective however the …