Natural product derived phytochemicals in managing acute lung injury by multiple mechanisms
YQ He, CC Zhou, LY Yu, L Wang, JL Deng… - Pharmacological …, 2021 - Elsevier
Acute lung injury (ALI) and its more severe form, acute respiratory distress syndrome
(ARDS) as common life-threatening lung diseases with high mortality rates are mostly …
(ARDS) as common life-threatening lung diseases with high mortality rates are mostly …
Mesenchymal stromal cells for acute respiratory distress syndrome (ARDS), sepsis, and COVID-19 infection: optimizing the therapeutic potential
E Gorman, J Millar, D McAuley… - Expert review of …, 2021 - Taylor & Francis
Introduction: Mesenchymal stromal (stem) cell (MSC) therapies are emerging as a promising
therapeutic intervention in patients with Acute Respiratory Distress Syndrome (ARDS) and …
therapeutic intervention in patients with Acute Respiratory Distress Syndrome (ARDS) and …
Acute lung injury in patients with COVID‐19 infection
L Li, Q Huang, DC Wang, DH Ingbar… - Clinical and …, 2020 - Wiley Online Library
Abstract During the 2020 Spring Festival in China, the outbreak of a novel coronavirus,
named COVID‐19 by WHO, brought on a worldwide panic. According to the clinical data of …
named COVID‐19 by WHO, brought on a worldwide panic. According to the clinical data of …
Manipulation of macrophage polarization by peptide-coated gold nanoparticles and its protective effects on acute lung injury
L Wang, H Zhang, L Sun, W Gao, Y Xiong, A Ma… - Journal of …, 2020 - Springer
Background Macrophage polarization and reprogramming in the lung play a critical role in
the initiation, development and progression of acute lung injury (ALI). Regulating the …
the initiation, development and progression of acute lung injury (ALI). Regulating the …
Endothelial cell‐derived extracellular vesicles expressing surface VCAM1 promote sepsis‐related acute lung injury by targeting and reprogramming monocytes
L Wang, Y Tang, J Tang, X Liu, S Zi, S Li… - Journal of …, 2024 - Wiley Online Library
Acute lung injury (ALI)/acute respiratory distress syndrome (ARDS) is a common life‐
threatening syndrome with no effective pharmacotherapy. Sepsis‐related ARDS is the main …
threatening syndrome with no effective pharmacotherapy. Sepsis‐related ARDS is the main …
Repair of acute respiratory distress syndrome by stromal cell administration (REALIST) trial: a phase 1 trial
E Gorman, M Shankar-Hari, P Hopkins… - …, 2021 - thelancet.com
Abstract Background Mesenchymal stromal cells (MSCs) may be of benefit in acute
respiratory distress syndrome (ARDS) due to immunomodulatory, reparative, and …
respiratory distress syndrome (ARDS) due to immunomodulatory, reparative, and …
Airway redox homeostasis and inflammation gone awry: from molecular pathogenesis to emerging therapeutics in respiratory pathology
J Checa, JM Aran - International journal of molecular sciences, 2020 - mdpi.com
As aerobic organisms, we are continuously and throughout our lifetime subjected to an
oxidizing atmosphere and, most often, to environmental threats. The lung is the internal …
oxidizing atmosphere and, most often, to environmental threats. The lung is the internal …
Novel biomarkers for acute respiratory distress syndrome: genetics, epigenetics and transcriptomics
F Zheng, Y Pan, Y Yang, C Zeng, X Fang… - Biomarkers in …, 2022 - Future Medicine
Acute respiratory distress syndrome (ARDS) can be induced by multiple clinical factors,
including sepsis, acute pancreatitis, trauma, intestinal ischemia/reperfusion and burns …
including sepsis, acute pancreatitis, trauma, intestinal ischemia/reperfusion and burns …
mRNA-based therapeutics: looking beyond COVID-19 vaccines
H Parhiz, EN Atochina-Vasserman, D Weissman - The Lancet, 2024 - thelancet.com
Recent advances in mRNA technology and its delivery have enabled mRNA-based
therapeutics to enter a new era in medicine. The rapid, potent, and transient nature of mRNA …
therapeutics to enter a new era in medicine. The rapid, potent, and transient nature of mRNA …
Mesenchymal stromal cells: an antimicrobial and host-directed therapy for complex infectious diseases
TD Shaw, AD Krasnodembskaya… - Clinical microbiology …, 2021 - Am Soc Microbiol
There is an urgent need for new antimicrobial strategies for treating complex infections and
emerging pathogens. Human mesenchymal stromal cells (MSCs) are adult multipotent cells …
emerging pathogens. Human mesenchymal stromal cells (MSCs) are adult multipotent cells …