Increases in the prevalence of noncommunicable diseases (NCDs), particularly
cardiometabolic diseases such as cardiovascular disease, stroke and diabetes, and their …

Antisense oligonucleotides (ASOs) are promising tools for gene silencing and have been
exploited as therapeutics for human disease. However, delivery of therapeutic ASOs to …

Background The burden of cardiovascular diseases is increasing in India, but a systematic
understanding of its distribution and time trends across all the states is not readily available …

Rationale: Hypertension represents a major risk factor for stroke, myocardial infarction, and
heart failure and affects 30% of the adult population. Mitochondrial dysfunction contributes to …

The circadian system, that is ubiquitous across species, generates∼ 24 h rhythms in
virtually all biological processes, and allows them to anticipate and adapt to the 24 h …

Smart wearables provide an opportunity to monitor health in daily life and are emerging as
potential tools for detecting cardiovascular disease (CVD). Wearables such as fitness bands …

Homocysteine (Hcy) metabolism is crucial for regulating methionine availability, protein
homeostasis, and DNA-methylation presenting, therefore, key pathways in post-genomic …

Ischaemic heart disease is a leading cause of death worldwide. Injury to the heart is
followed by loss of the damaged cardiomyocytes, which are replaced with fibrotic scar …

Importance Cardiovascular disease (CVD) is the leading cause of death in the United
States, but regional variation within the United States is large. Comparable and consistent …

Background: Individuals of South Asian ancestry represent 23% of the global population,
corresponding to 1.8 billion people, and have substantially higher risk of atherosclerotic …