Nicotinic, glutamatergic and dopaminergic synaptic transmission and plasticity in the mesocorticolimbic system: focus on nicotine effects

F Pistillo, F Clementi, M Zoli, C Gotti - Progress in neurobiology, 2015 - Elsevier
Cigarette smoking is currently the leading cause of preventable deaths and disability
throughout the world, being responsible for about five million premature deaths/year …

[HTML][HTML] Neurobiological determinants of tobacco smoking in schizophrenia

AM Lucatch, DJE Lowe, RC Clark, K Kozak… - Frontiers in …, 2018 - frontiersin.org
Purpose of review: To provide an overview of the underlying neurobiology of tobacco
smoking in schizophrenia, and implications for treatment of this comorbidity. Recent findings …

[HTML][HTML] Effects of chronic inhalation of electronic cigarette vapor containing nicotine on neurotransmitters in the frontal cortex and striatum of C57BL/6 mice

F Alasmari, LE Crotty Alexander… - Frontiers in …, 2019 - frontiersin.org
Electronic (E)-cigarettes are the latest form of nicotine delivery device and are highly popular
in the general population. It is currently unknown whether vaping E-cigarettes (E-CIGs) …

[HTML][HTML] Transcriptome-wide gene-gene interaction associations elucidate pathways and functional enrichment of complex traits

LM Evans, CH Arehart, AD Grotzinger, TJ Mize… - PLoS …, 2023 - journals.plos.org
It remains unknown to what extent gene-gene interactions contribute to complex traits. Here,
we introduce a new approach using predicted gene expression to perform exhaustive …

Involvement of glutamatergic and GABAergic systems in nicotine dependence: Implications for novel pharmacotherapies for smoking cessation

X Li, S Semenova, MS D'Souza, AK Stoker… - Neuropharmacology, 2014 - Elsevier
Tobacco smoking continues to be a major global health hazard despite significant public
awareness of its harmful consequences. Although several treatment options are currently …

Regional GABA concentrations modulate inter-network resting-state functional connectivity

X Chen, X Fan, Y Hu, C Zuo… - Cerebral …, 2019 - academic.oup.com
Coordinated activity within and differential activity between large-scale neuronal networks
such as the default mode network (DMN) and the control network (CN) is a critical feature of …

The co-use of nicotine and prescription psychostimulants: A review of their behavioral and neuropharmacological interactions

KR McNealy, L Weyrich, RA Bevins - Drug and Alcohol Dependence, 2023 - Elsevier
Background Nicotine is commonly co-used with other psychostimulants. These high co-use
rates have prompted much research on interactions between nicotine and psychostimulant …

[HTML][HTML] The role of ghrelin/GHS-R1A signaling in nonalcohol drug addictions

M Sustkova-Fiserova, C Charalambous… - International Journal of …, 2022 - mdpi.com
Drug addiction causes constant serious health, social, and economic burden within the
human society. The current drug dependence pharmacotherapies, particularly relapse …

[HTML][HTML] Understanding the neurobiological effects of drug abuse: Lessons from zebrafish models

TE Müller, BD Fontana, KT Bertoncello… - Progress in Neuro …, 2020 - Elsevier
Drug abuse and brain disorders related to drug comsumption are public health problems
with harmful individual and social consequences. The identification of therapeutic targets …

Hyperconnectivity of two separate long-range cholinergic systems contributes to the reorganization of the brain functional connectivity during nicotine withdrawal in …

LLG Carrette, A Kimbrough, PA Davoudian, AC Kwan… - Eneuro, 2023 - eneuro.org
Chronic nicotine results in dependence with withdrawal symptoms on discontinuation of use,
through desensitization of nicotinic acetylcholine receptors and altered cholinergic …