Skeletal muscle atrophy: From mechanisms to treatments
L Yin, N Li, W Jia, N Wang, M Liang, X Yang… - Pharmacological …, 2021 - Elsevier
Skeletal muscle is a crucial tissue for movement, gestural assistance, metabolic
homeostasis, and thermogenesis. It makes up approximately 40% of the total body weight …
homeostasis, and thermogenesis. It makes up approximately 40% of the total body weight …
[HTML][HTML] Molecular mechanisms of inflammation in sarcopenia: diagnosis and therapeutic update
GE Jimenez-Gutierrez, LE Martínez-Gómez… - Cells, 2022 - mdpi.com
Sarcopenia is generally an age-related condition that directly impacts the quality of life. It is
also related to chronic diseases such as metabolic dysfunction associated with diabetes and …
also related to chronic diseases such as metabolic dysfunction associated with diabetes and …
[HTML][HTML] Potential therapeutic strategies for skeletal muscle atrophy
L Huang, M Li, C Deng, J Qiu, K Wang, M Chang… - Antioxidants, 2022 - mdpi.com
The maintenance of muscle homeostasis is vital for life and health. Skeletal muscle atrophy
not only seriously reduces people's quality of life and increases morbidity and mortality, but …
not only seriously reduces people's quality of life and increases morbidity and mortality, but …
[HTML][HTML] The effect of omega-3 fatty acids on sarcopenia: mechanism of action and potential efficacy
A Therdyothin, N Phiphopthatsanee, M Isanejad - Marine Drugs, 2023 - mdpi.com
Sarcopenia, a progressive disease characterized by a decline in muscle strength, quality,
and mass, affects aging population worldwide, leading to increased morbidity and mortality …
and mass, affects aging population worldwide, leading to increased morbidity and mortality …
[HTML][HTML] DHA alleviates diet-induced skeletal muscle fiber remodeling via FTO/m6A/DDIT4/PGC1α signaling
W Chen, Y Chen, R Wu, G Guo, Y Liu, B Zeng, X Liao… - BMC biology, 2022 - Springer
Background Obesity leads to a decline in the exercise capacity of skeletal muscle, thereby
reducing mobility and promoting obesity-associated health risks. Dietary intervention has …
reducing mobility and promoting obesity-associated health risks. Dietary intervention has …
[HTML][HTML] Advances in nutritional supplementation for sarcopenia management
S Liu, L Zhang, S Li - Frontiers in Nutrition, 2023 - frontiersin.org
Sarcopenia is a syndrome characterized by a decline in muscular mass, strength, and
function with advancing age. The risk of falls, fragility, hospitalization, and death is …
function with advancing age. The risk of falls, fragility, hospitalization, and death is …
[HTML][HTML] Is dexamethasone-induced muscle atrophy an alternative model for naturally aged sarcopenia model?
BYH Wang, AWT Hsiao, N Wong, YF Chen… - Journal of Orthopaedic …, 2023 - Elsevier
Background Primary sarcopenia is usually known as age-related skeletal muscle loss;
however, other factors like endocrine, lifestyle and inflammation can also cause muscle loss …
however, other factors like endocrine, lifestyle and inflammation can also cause muscle loss …
Linolenic acid ameliorates sarcopenia in C. elegans by promoting mitophagy and fighting oxidative stress
L Zhang, X Zhang, T Zhang, Y Guo, W Pei, R Liu… - Food & Function, 2023 - pubs.rsc.org
Sarcopenia is a syndrome of age-related loss of muscle mass and strength that seriously
affects human health, and there are currently no effective drugs to treat the disease …
affects human health, and there are currently no effective drugs to treat the disease …
Strategies to protect against age-related mitochondrial decay: Do natural products and their derivatives help?
F Visioli, A Ingram, JS Beckman, KR Magnusson… - Free Radical Biology …, 2022 - Elsevier
Mitochondria serve vital roles critical for overall cellular function outside of energy
transduction. Thus, mitochondrial decay is postulated to be a key factor in aging and in age …
transduction. Thus, mitochondrial decay is postulated to be a key factor in aging and in age …
[HTML][HTML] Cancer-associated muscle wasting—candidate mechanisms and molecular pathways
VS Armstrong, LW Fitzgerald, OF Bathe - International Journal of …, 2020 - mdpi.com
Excessive muscle loss is commonly observed in cancer patients and its association with
poor prognosis has been well-established. Cancer-associated sarcopenia differs from age …
poor prognosis has been well-established. Cancer-associated sarcopenia differs from age …