Nearly six million people in United States have heart failure. Fifty percent of these people
have normal left ventricular (LV) systolic heart function but abnormal diastolic function due to …

Cancer-associated fibroblasts (CAFs) are a major constituent of the tumor microenvironment
(TME) and an important contributor to cancer progression and therapeutic resistance …

We have evaluated the role of mitochondrial oxidative stress and its association with
endoplasmic reticulum (ER) stress activation in the progression of obesity-related …

Aging is a complex and progressive process that involves physiological and metabolic
deterioration in every organ and system. Cardiovascular diseases are one of the most …

More than one million new cases of breast cancer are diagnosed worldwide each year and
more than 400,000 deaths are caused by the disease. The origin of this pathology is …

Remodeling, diastolic dysfunction, and arterial stiffness are some of the alterations through
which obesity affects the cardiovascular system. Fibrosis and inflammation are important …

Human feeding behavior and lifestyle are gradually being altered, favoring the development
of metabolic diseases, particularly type 2 diabetes and obesity. Leptin is produced by the …

Cardiac fibrosis contributes to the pathogenesis of atrial fibrillation (AF). The molecular
mechanisms underlying the cardiac fibrosis remain unclear. However, Ras association …

Abstract Context: Fruit vinegars (FVs) are used in Mediterranean folk medicine for their
hypolipidemic and weight-reducing properties. Objective: To investigate the preventive …

Idiopathic pulmonary fibrosis (IPF) is a progressive, fibrotic interstitial pneumonia with high
mortality. Melatonin, a hormone predominantly secreted by the pineal gland, has been …