Recent strategies to develop innovative photosensitizers for enhanced photodynamic therapy
TC Pham, VN Nguyen, Y Choi, S Lee, J Yoon - Chemical reviews, 2021 - ACS Publications
This review presents a robust strategy to design photosensitizers (PSs) for various species.
Photodynamic therapy (PDT) is a photochemical-based treatment approach that involves the …
Photodynamic therapy (PDT) is a photochemical-based treatment approach that involves the …
Transition metal complexes and photodynamic therapy from a tumor-centered approach: challenges, opportunities, and highlights from the development of TLD1433
Transition metal complexes are of increasing interest as photosensitizers in photodynamic
therapy (PDT) and, more recently, for photochemotherapy (PCT). In recent years, Ru (II) …
therapy (PDT) and, more recently, for photochemotherapy (PCT). In recent years, Ru (II) …
Targeted photoredox catalysis in cancer cells
Hypoxic tumours are a major problem for cancer photodynamic therapy. Here, we show that
photoredox catalysis can provide an oxygen-independent mechanism of action to combat …
photoredox catalysis can provide an oxygen-independent mechanism of action to combat …
Stimuli-responsive therapeutic metallodrugs
The success of platinum-based anticancer agents has motivated the exploration of novel
metal-based drugs for several decades, whereas problems such as drug-resistance and …
metal-based drugs for several decades, whereas problems such as drug-resistance and …
Critical overview of the use of Ru (II) polypyridyl complexes as photosensitizers in one-photon and two-photon photodynamic therapy
Conspectus Photodynamic Therapy (PDT) is an emerging technique to treat certain types of
cancer, bacterial, fungal, and viral infections, and skin diseases. In past years, different …
cancer, bacterial, fungal, and viral infections, and skin diseases. In past years, different …
The development of ruthenium (II) polypyridyl complexes and conjugates for in vitro cellular and in vivo applications
Ruthenium (II)[Ru (II)] polypyridyl complexes have been the focus of intense investigations
since work began exploring their supramolecular interactions with DNA. In recent years …
since work began exploring their supramolecular interactions with DNA. In recent years …
Transition metal complexes as photosensitisers in one-and two-photon photodynamic therapy
Photodynamic therapy (PDT) exploits light-activated compounds for therapeutic use. It relies
on a photosensitiser (PS) that is inactive in the absence of light. When irradiated, the PS …
on a photosensitiser (PS) that is inactive in the absence of light. When irradiated, the PS …
A mitochondria‐targeted photosensitizer showing improved photodynamic therapy effects under hypoxia
W Lv, Z Zhang, KY Zhang, H Yang, S Liu… - Angewandte Chemie …, 2016 - Wiley Online Library
Organelle‐targeted photosensitizers have been reported to be effective photodynamic
therapy (PDT) agents. In this work, we designed and synthesized two iridium (III) complexes …
therapy (PDT) agents. In this work, we designed and synthesized two iridium (III) complexes …
Combination of Ru (II) complexes and light: new frontiers in cancer therapy
The synergistic action of light, oxygen and a photosensitizer (PS) has found applications for
decades in medicine under the name of photodynamic therapy (PDT) for the treatment of …
decades in medicine under the name of photodynamic therapy (PDT) for the treatment of …
Highly charged ruthenium (II) polypyridyl complexes as lysosome‐localized photosensitizers for two‐photon photodynamic therapy
Photodynamic therapy (PDT) is a noninvasive medical technique that has received
increasing attention over the last years and been applied for the treatment of certain types of …
increasing attention over the last years and been applied for the treatment of certain types of …