Over the last two decades, hydrogen sulfide (H2S) has emerged as an endogenous
regulator of a broad range of physiological functions. H2S belongs to the class of molecules …

The prevalence of cerebrovascular disease increases with age, placing the elderly at a
greater lifetime risk for dementia. Vascular cognitive impairment (VCI) encompasses a …

An effective nanotherapeutic transport from the vasculature to the tumour is crucial for
cancer treatment with minimal side effects. Here we demonstrate that, in addition to the …

Delivering cancer therapeutics to tumors necessitates their escape from the surrounding
blood vessels. Tumor vasculatures are not always sufficiently leaky. Herein, we engineer …

The blood–retina barrier (BRB) is the term used to define the properties of the retinal
capillaries and the retinal pigment epithelium (RPE), which separate the systemic circulation …

The intestine plays an essential role in integrating immunity and nutrient digestion and
absorption. Adjacent intestinal epithelia form tight junctions (TJs) that are essential to the …

Angiogenesis is a highly coordinated process of formation of new blood vessels from pre-
existing blood vessels. The process of development of the proper vascular network is a …

Simple Summary The gastrointestinal tract is a complex organization of various types of
epithelial cells forming a single layer of the mucosal barrier, the host mucosal immune …

The blood–spinal cord barrier (BSCB), a physical barrier between the blood and spinal cord
parenchyma, prevents the toxins, blood cells, and pathogens from entering the spinal cord …

Endothelial dysfunction is a major contributing factor to diseases such as atherosclerosis,
diabetes mellitus, obesity, hypertension, acute lung injury, preeclampsia, among others …