Increased generation of reactive oxygen species in embryos cultured in vitro

Y Goto, Y Noda, T Mori, M Nakano - Free Radical Biology and Medicine, 1993 - Elsevier
Previous studies have suggested that oxygen toxicity is closely related to the developmental
blockage of embryos cultured in vitro. In this study, to obtain an actual proof of the increase …

Involvement of superoxide radicals in the mouse two‐cell block

Y Noda, H Matsumoto, Y Umaoka… - Molecular …, 1991 - Wiley Online Library
The effect of oxygen toxicity on the development of mammalian embryos was asssessed by
the use of superoxide dismutase (SOD), a potent scavenger of superoxide radicals. Mouse …

The effect of melatonin on in vitro fertilization and embryo development in mice

B Ishizuka, Y Kuribayashi, K Murai… - Journal of pineal …, 2000 - Wiley Online Library
To examine the effect of melatonin on in vitro fertilization and embryonic development,
mouse embryos after insemination in vitro were cultured in a physiological medium with or …

Gene expression in pre-implantation mammalian embryos

GA Schultz, S Heyner - Mutation research/Reviews in Genetic Toxicology, 1992 - Elsevier
The pre-implantation mammalian embryo is initially under the control of maternal
informational macromolecules that are accumulated during oogenesis. Subsequently, the …

Insulin and insulin-like growth factor-I promote rabbit blastocyst development and prevent apoptosis

A Herrler, CA Krusche, HM Beier - Biology of reproduction, 1998 - academic.oup.com
Insulin as well as insulin-like growth factor-I (IGF-I) promote early embryo development, and
IGF-I binds to the coats of preimplantation rabbit embryos. As the IGF-I receptor is expressed …

Effects of superovulation, embryo recovery, culture system and embryo transfer on development of rabbit embryos in vivo and in vitro

EW Carney, RH Foote - Reproduction, 1990 - rep.bioscientifica.com
Uninterrupted development of rabbit embryos in vivo was studied in 7 superovulated and 7
normally ovulating (GnRH-treated) does, while another 7 does were superovulated and 1 …

Purification of an embryotrophic factor from commercial bovine serum albumin and its identification as citrate

CW Gray, PM Morgan, MT Kane - Reproduction, 1992 - rep.bioscientifica.com
A factor of low M r with growth-promoting effects on rabbit embryos was extracted and
purified from commercial bovine serum albumin (BSA). This embryotrophic factor was …

Novel human endometrial cell line promotes blastocyst development

NN Desai, EA Kennard, DA Kniss, CI Friedman - Fertility and sterility, 1994 - Elsevier
Objective To test and contrast the embryotrophic potential of an established human
endometrial cell line to that of two other epithelial cell types: human oviduct and African …

Development of preimplantation goat (Capra hircus) embryos in vivo and in vitro

D Sakkas, PA Batt, AWN Cameron - Reproduction, 1989 - rep.bioscientifica.com
Preimplantation goat embryos were cultured with or without goat oviduct epithelial cells in
Earle's 199 medium+ 10% goat serum (E199+ 10% GS), and in three different simple …

Effect of visual light on in vitro embryonic development in the hamster

Y Umaoka, Y Noda, T Nakayama, K Narimoto, T Mori… - Theriogenology, 1992 - Elsevier
The effect of light exposure during collection and culture of hamster embryos on their
subsequent development in vitro was examined. When embryos were collected under dark …