The role of prostaglandins and other eicosanoids in the gastrointestinal tract

D Wang, JR Mann, RN Dubois - Gastroenterology, 2005 - Elsevier
Nonsteroidal anti-inflammatory drugs (NSAIDs) are generally prescribed to ameliorate
symptoms associated with acute pain and chronic inflammatory diseases such as arthritis …

Colon cancer: genomics and apoptotic events

C Rupnarain, Z Dlamini, S Naicker, K Bhoola - 2004 - degruyter.com
Colon cancer is the third most common cancer globally. The risk of developing colon cancer
is influenced by a number of factors that include age and diet, but is primarily a genetic …

Genetic variants in cyclooxygenase-2: Expression and risk of gastric cancer and its precursors in a Chinese population

F Liu, K Pan, X Zhang, Y Zhang, L Zhang, J Ma… - Gastroenterology, 2006 - Elsevier
Background & Aims: To screen the genetic variants in cyclooxygenase-2 (COX-2), and
evaluate their effects on COX-2 expression and risk of gastric cancer (GC) and its …

San-Huang-Xie-Xin-Tang inhibits Helicobacter pylori-induced inflammation in human gastric epithelial AGS cells

YT Shih, DC Wu, CM Liu, YC Yang, J Chen… - Journal of …, 2007 - Elsevier
Helicobacter pylori infection leads to gastroduodenal inflammation, peptic ulceration, gastric
lymphoma and gastric cancer. Certain herbal remedies have been used to treat gastric …

[HTML][HTML] Characteristics of gastric precancerous conditions and Helicobacter pylori infection among dyspeptic patients in north-eastern Iran: is endoscopic biopsy and …

A Esmaeilzadeh, L Goshayeshi, R Bergquist, L Jarahi… - BMC cancer, 2021 - Springer
Background Early detection and appropriate treatment of precancerous, mucosal changes
could significantly decrease the prevalence of life-threatening gastric cancer. Biopsy of the …

Helicobacter pylori , cyclooxygenase-2 and evolution of gastric lesions: results from an intervention trial in China

Y Zhang, K Pan, L Zhang, J Ma, T Zhou, J Li… - …, 2015 - academic.oup.com
To investigate the role of cyclooxygenase (COX)-2/prostaglandin E 2 (PGE 2) in the process
of Helicobacter pylori-induced gastric carcinogenesis, a prospective study based on an …

Cyclooxygenase‐2 and tumor biology

S Kanaoka, T Takai, K Yoshida - Advances in clinical chemistry, 2007 - Elsevier
There is now substantial evidence for the role of cyclooxygenase (COX)‐2 in causation and
prevention of cancer. Selective COX‐2 inhibitors (coxibs) were considered attractive …

[HTML][HTML] Non-steroidal anti-inflammatory drugs in prevention of gastric cancer

Y Dai, WH Wang - World journal of gastroenterology: WJG, 2006 - ncbi.nlm.nih.gov
Non-steroidal anti-inflammatory drugs (NSAIDs) including cyclooxygenase 2 (COX-2)
selective inhibitors, are potential agents for the chemoprevention of gastric cancer …

[HTML][HTML] Association of cyclooxygenase-2 expression with Hp-cagA infection in gastric cancer

XL Guo, LE Wang, SY Du, CL Fan, L Li… - World Journal of …, 2003 - ncbi.nlm.nih.gov
AIM: To observe the expression of cyclooxygenase-2 (COX-2) and to investigate the
association between COX-2 expression and infection with cytotoxic-associated gene A …

Natural products as gastroprotective and antiulcer agents: Recent developments

R Tundis, MR Loizzo, M Bonesi… - Natural Product …, 2008 - journals.sagepub.com
Peptic ulcer, one of the most common gastrointestinal diseases, is a chronic inflammatory
disease characterized by ulceration in the regions of the upper gastrointestinal tract where …