[HTML][HTML] Biomechanical microenvironment in peripheral nerve regeneration: from pathophysiological understanding to tissue engineering development
Peripheral nerve injury (PNI) caused by trauma, chronic disease and other factors may lead
to partial or complete loss of sensory, motor and autonomic functions, as well as neuropathic …
to partial or complete loss of sensory, motor and autonomic functions, as well as neuropathic …
[HTML][HTML] Hippo pathway in Schwann cells and regeneration of peripheral nervous system
J Wang, H Chen, W Hou, Q Han, Z Wang - Developmental …, 2023 - karger.com
Hippo pathway is an evolutionarily conserved signaling pathway comprising a series of
MST/LATS kinase complexes. Its key transcriptional coactivators YAP and TAZ regulate …
MST/LATS kinase complexes. Its key transcriptional coactivators YAP and TAZ regulate …
Integration of genetically engineered virus nanofibers and fibrin to form injectable fibrous neuron-rich hydrogels and enable neural differentiation
Y Chen, X Liu, M Yang, W Sun, C Mao - Journal of Materials Chemistry …, 2023 - pubs.rsc.org
Peripheral nerve injury (PNI) results in persistent pain, a burning sensation, tingling, or
complete loss of sensation. Treating large nerve defects is a major challenge, and the use of …
complete loss of sensation. Treating large nerve defects is a major challenge, and the use of …
Molecular and regenerative characterization of repair and non-repair Schwann cells
T Suzuki, K Kadoya, T Endo, N Iwasaki - Cellular and molecular …, 2023 - Springer
Although evidence has accumulated to indicate that Schwann cells (SCs) differentiate into
repair SCs (RSCs) upon injury and that the unique phenotype of these cells allow them to …
repair SCs (RSCs) upon injury and that the unique phenotype of these cells allow them to …
Effect of electrical stimulation on nerve-guided facial nerve regeneration
G Choe, UG Han, S Ye, S Kang, J Yoo… - ACS Biomaterials …, 2023 - ACS Publications
This study aimed to investigate the effect of electrical stimulation on poly (d, l-lactide-co-ε-
caprolactone) nerve guidance conduits (NGCs) in promoting the recovery of facial function …
caprolactone) nerve guidance conduits (NGCs) in promoting the recovery of facial function …
α‐Asarone attenuates chronic sciatica by inhibiting peripheral sensitization and promoting neural repair
D Zhang, X Li, B Jing, Z Chen, H Shi… - Phytotherapy …, 2023 - Wiley Online Library
This study explored the therapeutic effect of α‐asarone on chronic sciatica. Thirty‐two
Sprague–Dawley (SD) rats were divided into four groups: the sham group, chronic …
Sprague–Dawley (SD) rats were divided into four groups: the sham group, chronic …
Dual Crosslinked Antioxidant Mixture of Poly (vinyl alcohol) and Cerium Oxide Nanoparticles as a Bioink for 3D Bioprinting
Three-dimensional (3D) bioprinting has made it possible to fabricate structures with intricate
morphologies and architectures, which is considered difficult to do when using other …
morphologies and architectures, which is considered difficult to do when using other …
[HTML][HTML] Graphene-based nanomaterials for peripheral nerve regeneration
D Convertino, ML Trincavelli, C Giacomelli… - Frontiers in …, 2023 - ncbi.nlm.nih.gov
Emerging nanotechnologies offer numerous opportunities in the field of regenerative
medicine and have been widely explored to design novel scaffolds for the regeneration and …
medicine and have been widely explored to design novel scaffolds for the regeneration and …
Biomimetic-inspired piezoelectric ovalbumin/BaTiO3 scaffolds synergizing with anisotropic topology for modulating Schwann cell and DRG behavior
H Gao, Y Liu, H Shen, W Guan, S Sun, T Zheng… - International Journal of …, 2024 - Elsevier
The treatment of peripheral nerve injury is a clinical challenge that tremendously affected the
patients' health and life. Anisotropic topographies and electric cues can simulate the …
patients' health and life. Anisotropic topographies and electric cues can simulate the …
[HTML][HTML] Growth factors: Bioactive macromolecular drugs for peripheral nerve injury treatment–Molecular mechanisms and delivery platforms
T Wan, FS Zhang, MY Qin, HR Jiang, M Zhang… - Biomedicine & …, 2024 - Elsevier
Bioactive macromolecular drugs known as Growth Factors (GFs), approved by the Food and
Drug Administration (FDA), have found successful application in clinical practice. They hold …
Drug Administration (FDA), have found successful application in clinical practice. They hold …