[HTML][HTML] Biomechanical microenvironment in peripheral nerve regeneration: from pathophysiological understanding to tissue engineering development

L Kong, X Gao, Y Qian, W Sun, Z You, C Fan - Theranostics, 2022 - ncbi.nlm.nih.gov
Peripheral nerve injury (PNI) caused by trauma, chronic disease and other factors may lead
to partial or complete loss of sensory, motor and autonomic functions, as well as neuropathic …

[HTML][HTML] Hippo pathway in Schwann cells and regeneration of peripheral nervous system

J Wang, H Chen, W Hou, Q Han, Z Wang - Developmental …, 2023 - karger.com
Hippo pathway is an evolutionarily conserved signaling pathway comprising a series of
MST/LATS kinase complexes. Its key transcriptional coactivators YAP and TAZ regulate …

Integration of genetically engineered virus nanofibers and fibrin to form injectable fibrous neuron-rich hydrogels and enable neural differentiation

Y Chen, X Liu, M Yang, W Sun, C Mao - Journal of Materials Chemistry …, 2023 - pubs.rsc.org
Peripheral nerve injury (PNI) results in persistent pain, a burning sensation, tingling, or
complete loss of sensation. Treating large nerve defects is a major challenge, and the use of …

Molecular and regenerative characterization of repair and non-repair Schwann cells

T Suzuki, K Kadoya, T Endo, N Iwasaki - Cellular and molecular …, 2023 - Springer
Although evidence has accumulated to indicate that Schwann cells (SCs) differentiate into
repair SCs (RSCs) upon injury and that the unique phenotype of these cells allow them to …

Effect of electrical stimulation on nerve-guided facial nerve regeneration

G Choe, UG Han, S Ye, S Kang, J Yoo… - ACS Biomaterials …, 2023 - ACS Publications
This study aimed to investigate the effect of electrical stimulation on poly (d, l-lactide-co-ε-
caprolactone) nerve guidance conduits (NGCs) in promoting the recovery of facial function …

α‐Asarone attenuates chronic sciatica by inhibiting peripheral sensitization and promoting neural repair

D Zhang, X Li, B Jing, Z Chen, H Shi… - Phytotherapy …, 2023 - Wiley Online Library
This study explored the therapeutic effect of α‐asarone on chronic sciatica. Thirty‐two
Sprague–Dawley (SD) rats were divided into four groups: the sham group, chronic …

Dual Crosslinked Antioxidant Mixture of Poly (vinyl alcohol) and Cerium Oxide Nanoparticles as a Bioink for 3D Bioprinting

N Rizwana, N Maslekar, K Chatterjee… - ACS Applied Nano …, 2023 - ACS Publications
Three-dimensional (3D) bioprinting has made it possible to fabricate structures with intricate
morphologies and architectures, which is considered difficult to do when using other …

[HTML][HTML] Graphene-based nanomaterials for peripheral nerve regeneration

D Convertino, ML Trincavelli, C Giacomelli… - Frontiers in …, 2023 - ncbi.nlm.nih.gov
Emerging nanotechnologies offer numerous opportunities in the field of regenerative
medicine and have been widely explored to design novel scaffolds for the regeneration and …

Biomimetic-inspired piezoelectric ovalbumin/BaTiO3 scaffolds synergizing with anisotropic topology for modulating Schwann cell and DRG behavior

H Gao, Y Liu, H Shen, W Guan, S Sun, T Zheng… - International Journal of …, 2024 - Elsevier
The treatment of peripheral nerve injury is a clinical challenge that tremendously affected the
patients' health and life. Anisotropic topographies and electric cues can simulate the …

[HTML][HTML] Growth factors: Bioactive macromolecular drugs for peripheral nerve injury treatment–Molecular mechanisms and delivery platforms

T Wan, FS Zhang, MY Qin, HR Jiang, M Zhang… - Biomedicine & …, 2024 - Elsevier
Bioactive macromolecular drugs known as Growth Factors (GFs), approved by the Food and
Drug Administration (FDA), have found successful application in clinical practice. They hold …