Epitranscriptomic RNA methylation in plant development and abiotic stress responses

J Hu, S Manduzio, H Kang - Frontiers in Plant Science, 2019 - frontiersin.org
Recent advances in methylated RNA immunoprecipitation followed by sequencing and
mass spectrometry have revealed widespread chemical modifications on mRNAs …

Distinct Roles of m5C RNA Methyltransferase NSUN2 in Major Gynecologic Cancers

L Wang, J Zhang, Y Su, Y Maimaitiyiming… - Frontiers in …, 2022 - frontiersin.org
RNA methylation has recently emerged as an important category of epigenetic
modifications, which plays diverse physiopathological roles in various cancers. Recent …

Role of main RNA methylation in hepatocellular carcinoma: N6-methyladenosine, 5-methylcytosine, and N1-methyladenosine

Y Xu, M Zhang, Q Zhang, X Yu, Z Sun, Y He… - Frontiers in cell and …, 2021 - frontiersin.org
RNA methylation is considered a significant epigenetic modification, a process that does not
alter gene sequence but may play a necessary role in multiple biological processes, such as …

The diversity and functions of plant RNA modifications: what we know and where we go from here

B Sharma, W Prall, G Bhatia… - Annual Review of Plant …, 2023 - annualreviews.org
Since the discovery of the first ribonucleic acid (RNA) modifications in transfer RNAs (tRNAs)
and ribosomal RNAs (rRNAs), scientists have been on a quest to decipher the identities and …

m5C-related lncRNAs predict overall survival of patients and regulate the tumor immune microenvironment in lung adenocarcinoma

J Pan, Z Huang, Y Xu - Frontiers in cell and developmental biology, 2021 - frontiersin.org
Long non-coding RNAs (lncRNAs), which are involved in the regulation of RNA methylation,
can be used to evaluate tumor prognosis. lncRNAs are closely related to the prognosis of …

Analysis of RNA modifications by second-and third-generation deep sequencing: 2020 update

Y Motorin, V Marchand - Genes, 2021 - mdpi.com
The precise mapping and quantification of the numerous RNA modifications that are present
in tRNAs, rRNAs, ncRNAs/miRNAs, and mRNAs remain a major challenge and a top priority …

The crucial mechanism and therapeutic implication of RNA methylation in bone pathophysiology

C Yang, Z Dong, Z Ling, Y Chen - Ageing research reviews, 2022 - Elsevier
Methylation is the most common posttranscriptional modification in cellular RNAs, which has
been reported to modulate the alteration of RNA structure for initiating relevant functions …

Cotranscriptional RNA processing and modification in plants

S Marquardt, E Petrillo, PA Manavella - The Plant Cell, 2023 - academic.oup.com
The activities of RNA polymerases shape the epigenetic landscape of genomes with
profound consequences for genome integrity and gene expression. A fundamental event …

Messenger RNA modifications in plants

L Shen, Z Liang, CE Wong, H Yu - Trends in Plant Science, 2019 - cell.com
Over 160 distinct RNA modifications are known and collectively termed the epitranscriptome.
Some of these modifications have been discovered in mRNA, uncovering a new layer of …

Advances in RNA cytosine-5 methylation: detection, regulatory mechanisms, biological functions and links to cancer

C Xue, Y Zhao, L Li - Biomarker Research, 2020 - Springer
As an important posttranscriptional modification of RNA, 5-methylcytosine (m 5 C) has
attracted increasing interest recently, with accumulating evidence suggesting the …