5-Methylcytosine (m5C) is a RNA modification that exists in tRNAs and rRNAs and was
recently found in mRNAs. Although it has been suggested to regulate diverse biological …

The recent advent of high-throughput sequencing technologies coupled with RNA
modifications detection methods has allowed the detection of RNA modifications at single …

The intrinsic cellular heterogeneity and molecular complexity of the mammalian nervous
system relies substantially on the dynamic nature and spatiotemporal patterning of gene …

Although covalent nucleotide modifications were first identified on the bases of transfer
RNAs (tRNAs) and ribosomal RNAs (rRNAs), a number of these epitranscriptome marks …

Among all reactive oxygen species (ROS), hydrogen peroxide (H2O2) takes a central role in
regulating plant development and responses to the environment. The diverse role of H2O2 …

Efforts have been directed to redesign crops with increased yield, stress adaptability, and
nutritional value through synthetic biology—the application of engineering principles to …

methylcytosine (m5C) is identified as an abundant and conserved modification in various
RNAs, including tRNAs, mRNAs, rRNAs, and other non-coding RNAs. The application of …

Cellular metabolism is an intricate network satisfying bioenergetic and biosynthesis
requirements of cells. Relevant studies have been constantly making inroads in our …

Background Post-transcriptional methylation modifications, including 5-methylcytosine
(m5C) modification, are closely related to the tumorigenesis of cancers. However, the mRNA …

The molecular machinery for protein synthesis is profoundly similar between plants and
other eukaryotes. Mechanisms of translational gene regulation are embedded into the …