Metabolic labeling of RNAs uncovers hidden features and dynamics of the Arabidopsis transcriptome

EX Szabo, P Reichert, MK Lehniger, M Ohmer… - The Plant …, 2020 - academic.oup.com
Transcriptome analysis by RNA sequencing (RNA-seq) has become an indispensable
research tool in modern plant biology. Virtually all RNA-seq studies provide a snapshot of …

[HTML][HTML] Epigenetic addition of m5C to HBV transcripts promotes viral replication and evasion of innate antiviral responses

S Ding, H Liu, L Liu, L Ma, Z Chen, M Zhu, L Liu… - Cell Death & …, 2024 - nature.com
Eukaryotic five-methylcytosine (m5C) is an important regulator of viral RNA splicing, stability,
and translation. However, its role in HBV replication remains largely unknown. In this study …

[HTML][HTML] Epigenome and epitranscriptome: potential resources for crop improvement

Q Hou, X Wan - International Journal of Molecular Sciences, 2021 - mdpi.com
Crop breeding faces the challenge of increasing food demand, especially under climatic
changes. Conventional breeding has relied on genetic diversity by combining alleles to …

[HTML][HTML] 5-methylcytosine RNA methylation regulators affect prognosis and tumor microenvironment in lung adenocarcinoma

T Liu, X Hu, C Lin, X Shi, Y He, J Zhang… - Annals of translational …, 2022 - ncbi.nlm.nih.gov
Background Accumulating evidence has shown that 5-methylcytosinec (m5C) RNA
methylation plays an essential role in tumorigenesis. However, the roles of m5C regulators …

The N1-Methyladenosine Methylome of Petunia mRNA

W Yang, J Meng, J Liu, B Ding, T Tan, Q Wei… - Plant …, 2020 - academic.oup.com
N1-methyladenosine is a unique type of base methylation in that it blocks Watson-Crick
base pairing and introduces a positive charge. m1A is prevalent in yeast and mammalian …

Post-transcriptional regulation of the oxidative stress response in plants

V Van Ruyskensvelde, F Van Breusegem… - Free Radical Biology …, 2018 - Elsevier
Due to their sessile lifestyle, plants can be exposed to several kinds of stresses that will
increase the production of reactive oxygen species (ROS), such as hydrogen peroxide …

[HTML][HTML] Transcriptome-Wide Annotation of m5C RNA Modifications Using Machine Learning

J Song, J Zhai, E Bian, Y Song, J Yu, C Ma - Frontiers in plant science, 2018 - frontiersin.org
The emergence of epitranscriptome opened a new chapter in gene regulation. 5-
methylcytosine (m5C), as an important post-transcriptional modification, has been identified …

ALY RNA-binding proteins are required for nucleocytosolic mRNA transport and modulate plant growth and development

C Pfaff, HF Ehrnsberger, M Flores-Tornero… - Plant …, 2018 - academic.oup.com
The regulated transport of mRNAs from the cell nucleus to the cytosol is a critical step linking
transcript synthesis and processing with translation. However, in plants, only a few of the …

ALYREF (Aly/REF export factor): A potential biomarker for predicting cancer occurrence and therapeutic efficacy

Y Zhao, C Xing, H Peng - Life Sciences, 2023 - Elsevier
Methylcytosine (m5C) methylation is present in almost all types of RNA as an essential
epigenetic modification. It is dynamically modulated by its associated enzymes, including …

[HTML][HTML] m5CRegpred: epitranscriptome target prediction of 5-methylcytosine (m5C) regulators based on sequencing features

Z He, J Xu, H Shi, S Wu - Genes, 2022 - mdpi.com
5-methylcytosine (m5C) is a common post-transcriptional modification observed in a variety
of RNAs. m5C has been demonstrated to be important in a variety of biological processes …