Background A program of normothermic ex situ liver perfusion (NESLiP) was developed to
facilitate better assessment and use of marginal livers, while minimizing cold ischemia …

Background & Aims Primary non-function and ischaemic cholangiopathy are the most feared
complications following donation-after-circulatory-death (DCD) liver transplantation. The aim …

After extensive experimentation, outcomes of a first clinical normothermic machine perfusion
(NMP) liver trial in the United Kingdom demonstrated feasibility and clear safety, with …

The European trial investigating normothermic ex vivo liver perfusion (NEVLP) as a
preservation technique for liver transplantation (LT) uses gelofusine, a non–US Food and …

Liver transplantation (LT) is a successful treatment for patients with liver failure. However,
organ shortage results in over 11% of patients losing their chance of a transplant attributed …

Liver transplantation was made a reality through the bravery, innovation, and persistence of
Dr. Thomas Starzl. His death in 2017, at the age of 90, makes us pause to consider how far …

Objective: To compare conventional low-temperature storage of transplant donor livers
[static cold storage (SCS)] with storage of the organs at physiological body temperature …

Organ transplantation is the most effective therapy for patients with end-stage disease.
Preservation solutions and techniques are crucial for donor organ quality, which is directly …

Organ transplantation is undergoing profound changes. Contraindications for donation have
been revised in order to better meet the organ demand. The use of lower-quality organs and …

Background & Aims Pretreatment of marginal organs by perfusion is a promising opportunity
to make more organs available for transplantation. Protection of human donation after …