The use of an acellular oxygen carrier in a human liver model of normothermic machine perfusion

RW Laing, RH Bhogal, L Wallace, Y Boteon… - …, 2017 - journals.lww.com
Background Normothermic machine perfusion of the liver (NMP-L) is a novel technique that
preserves liver grafts under near-physiological conditions while maintaining their normal …

[PDF][PDF] Normothermic machine perfusion of donor livers without the need for human blood products

APM Matton, LC Burlage, R van Rijn… - Liver …, 2018 - Wiley Online Library
Normothermic machine perfusion (NMP) enables viability assessment of donor livers prior to
transplantation. NMP is frequently performed by using human blood products including red …

[HTML][HTML] Introducing machine perfusion into routine clinical practice for liver transplantation in the United States: the moment has finally come

KP Croome - Journal of Clinical Medicine, 2023 - mdpi.com
While adoption of machine perfusion technologies into clinical practice in the United States
has been much slower than in Europe, recent changes in the transplant landscape as well …

Design, analysis, and pitfalls of clinical trials using ex situ liver machine perfusion: the international liver transplantation society consensus guidelines

PN Martins, MD Rizzari, D Ghinolfi, I Jochmans… - …, 2021 - journals.lww.com
Design, Analysis, and Pitfalls of Clinical Trials Using Ex S... : Transplantation Design, Analysis,
and Pitfalls of Clinical Trials Using Ex Situ Liver Machine Perfusion: The International Liver …

Machine perfusion for liver transplantation in the era of marginal organs—new kids on the block

Z Czigany, I Lurje, RH Tolba, UP Neumann… - Liver …, 2019 - Wiley Online Library
In the face of a critical organ shortage in the Western world, various strategies are employed
to expand the donor pool for orthotopic liver transplantation (OLT). Among them is the …

First human liver transplantation using a marginal allograft resuscitated by normothermic machine perfusion

T Perera, H Mergental, B Stephenson… - Liver …, 2016 - journals.lww.com
MATERIALS AND METHODS A liver graft offer from a 29‐year‐old male DCD donor was
initially accepted for transplantation by our center within the same allocation region …

[HTML][HTML] Continuous normothermic ex vivo kidney perfusion is superior to brief normothermic perfusion following static cold storage in donation after circulatory death …

JM Kaths, JY Cen, YM Chun, J Echeverri… - American Journal of …, 2017 - Elsevier
Hypothermic preservation is known to cause renal graft injury, especially in donation after
circulatory death (DCD) kidney transplantation. We investigated the impact of cold storage …

[PDF][PDF] Transient cold storage prior to normothermic liver perfusion may facilitate adoption of a novel technology

CDL Ceresa, D Nasralla, CJE Watson… - Liver …, 2019 - Wiley Online Library
Clinical adoption of normothermic machine perfusion (NMP) may be facilitated by simplifying
logistics and reducing costs. This can be achieved by cold storage of livers for transportation …

Organ preservation into the 2020s: the era of dynamic intervention

A Petrenko, M Carnevale, A Somov, J Osorio… - Transfusion Medicine …, 2019 - karger.com
Organ preservation has been of major importance ever since transplantation developed into
a global clinical activity. The relatively simple procedures were developed on a basic …

[PDF][PDF] Impact of donor age in donation after circulatory death liver transplantation: is the cutoff “60” still of relevance?

A Schlegel, I Scalera, MTPR Perera… - Liver …, 2018 - Wiley Online Library
Advanced donor age has been identified as a risk factor when combined with donor warm
ischemia time (WIT), eg, in donation after circulatory death (DCD). In several countries, DCD …