Viability testing during liver preservation
MP adds a further element of complexity in the process of assessing the quality of a liver
graft. Understanding the physiology of the parameters included in the different assessment …
graft. Understanding the physiology of the parameters included in the different assessment …
Extracellular vesicles from human liver stem cells reduce injury in an ex vivo normothermic hypoxic rat liver perfusion model
F Rigo, N De Stefano, V Navarro-Tableros… - …, 2018 - journals.lww.com
Background The gold standard for organ preservation before transplantation is static cold
storage, which is unable to fully protect suboptimal livers from ischemia/reperfusion injury …
storage, which is unable to fully protect suboptimal livers from ischemia/reperfusion injury …
Factors associated with short-and long-term liver graft survival in the United Kingdom: development of a UK donor liver index
D Collett, PJ Friend, CJE Watson - Transplantation, 2017 - journals.lww.com
Background A measure of donor liver quality, the donor liver index, was developed and
validated for the UK population of transplant recipients. Unlike previously proposed …
validated for the UK population of transplant recipients. Unlike previously proposed …
[PDF][PDF] Liver ex situ machine perfusion preservation: A review of the methodology and results of large animal studies and clinical trials
H Marecki, A Bozorgzadeh, RJ Porte… - Liver …, 2017 - Wiley Online Library
Ex vivo machine perfusion (MP) is a promising way to better preserve livers prior to
transplantation. Currently, no methodology has a verified benefit over simple cold storage …
transplantation. Currently, no methodology has a verified benefit over simple cold storage …
Ex vivo machine perfusion: current applications and future directions in liver transplantation
J Michelotto, JMGV Gassner, S Moosburner… - … archives of surgery, 2021 - Springer
Background Liver transplantation is the only curative treatment option for end-stage liver
disease; however, its use remains limited due to a shortage of suitable organs. In recent …
disease; however, its use remains limited due to a shortage of suitable organs. In recent …
Hypothermic machine preservation of the liver: state of the art
A Schlegel, X Muller, P Dutkowski - Current transplantation reports, 2018 - Springer
Abstract Purpose of Review In this review, we highlight which livers may benefit from
additional treatment before implantation and describe the concept of hypothermic machine …
additional treatment before implantation and describe the concept of hypothermic machine …
Perfusate enzymes and platelets indicate early allograft dysfunction after transplantation of normothermically preserved livers
A Weissenbacher, C Bogensperger, R Oberhuber… - …, 2022 - journals.lww.com
Background. Normothermic machine perfusion (NMP) has become a clinically established
tool to preserve livers in a near-physiological environment. However, little is known about …
tool to preserve livers in a near-physiological environment. However, little is known about …
[HTML][HTML] Normothermic ex vivo kidney perfusion for graft quality assessment prior to transplantation
JM Kaths, M Hamar, J Echeverri, I Linares… - American Journal of …, 2018 - Elsevier
Normothermic ex vivo kidney perfusion (NEVKP) represents a novel approach for graft
preservation and functional improvement in kidney transplantation. We investigated whether …
preservation and functional improvement in kidney transplantation. We investigated whether …
Viability assessment and transplantation of fatty liver grafts using end‐ischemic normothermic machine perfusion
D Patrono, R De Carlis, A Gambella… - Liver …, 2023 - journals.lww.com
End‐ischemic viability testing by normothermic machine perfusion (NMP) represents an
effective strategy to recover liver grafts having initially been discarded for liver …
effective strategy to recover liver grafts having initially been discarded for liver …
Primary nonfunction of the liver allograft
H Hartog, A Hann, MTPR Perera - Transplantation, 2022 - journals.lww.com
Severe allograft dysfunction, as opposed to the expected immediate function, following liver
transplantation is a major complication, and the clinical manifestations of such that lead to …
transplantation is a major complication, and the clinical manifestations of such that lead to …