Normothermic machine perfusion (NMP) has been shown to protect livers from injury
between procurement and transplantation in a randomized controlled trial, where the …

Despite improvements in postliver transplant outcomes through refinements in perioperative
management and surgical techniques, several changing trends in liver transplantation have …

RNA interference (RNAi) is a natural process of posttranscriptional gene regulation that has
raised a lot of attention culminating with the Nobel Prize in Medicine in 2006. RNAi‐based …

Regulatory T cells (Tregs) are crucial in maintaining tolerance. Hence, Treg immunotherapy
is an attractive therapeutic option in autoimmune diseases and organ transplantations …

Bile secretion and composition reflects the functional status of hepatocytes and
cholangiocytes. Bile composition can have a role in the assessment of donor grafts before …

A shortage of available organs for liver transplantation has led transplant surgeons and
researchers to seek for innovative approaches in hepatoprotection and improvement of …

In recent years, there has been growing interest in normothermic machine perfusion (NMP)
as a preservation method in liver transplantation. In most countries, because of a donor …

Livers from donors after circulatory death (DCD) are a promising option to increase the
donor pool, but their use is associated with higher complication rate and inferior graft …

Normothermic machine perfusion (NMP) aims to preserve organs ex vivo by simulating
physiological conditions such as body temperature. Recent advancements in NMP system …

Background: The increasing use of extended criteria donors (ECD) sets higher requirements
for graft preservation. Machine perfusion (MP) improves orthotopic liver transplantation …