The introduction of atypical antipsychotics (AAPs) since the discovery of its prototypical drug
clozapine has been a revolutionary pharmacological step for treating psychotic patients as …

Schizophrenia is a heterogenous and severe neuropsychiatric disorder that affects nearly
1% of the population worldwide. Antipsychotic drugs are the mainstay of treatment, but not …

INTRODUCTION Localized control of neuron activity is important for both brain research and
therapy. Chemogenetics is a method to control cellular activity by targeting defined cell …

Almost fifty years after its first introduction into clinical care, clozapine remains the only
evidence-based pharmacological option for treatment-resistant schizophrenia (TRS), which …

Clozapine is superior to other antipsychotics as a therapy for treatment-resistant
schizophrenia and schizoaffective disorder with increased risk of suicidal behavior. This …

Over the past decade, two independent technologies have emerged and been widely
adopted by the neuroscience community for remotely controlling neuronal activity …

Mole-fraction solubility of Clozapine (CLZ) in eleven mono-solvents (methanol, ethanol, n-
propanol, isopropanol, acetone, 1, 2-dichloroethane, benzene, toluene, N, N …

In this work, sub‐nanometer Co clusters anchored on porous nitrogen‐doped carbon (C─
N─ Co NCs) are successfully prepared by high‐temperature annealing and pre‐fabricated …

Codeine is used to relieve mild to moderately severe pain, and it belongs to the drug class of
opioid analgesics. Codeine has also been prescribed to prevent coughing, though the …

Aripiprazole was the first antipsychotic developed to possess agonist properties at
dopamine D2 autoreceptors, a groundbreaking strategy that presented a new vista for …