Bioinspired tissue-compliant hydrogels with multifunctions for synergistic surgery–photothermal therapy
W Jiang, Y Chen, L Zhao, J Xu, R Zhao… - Journal of Materials …, 2020 - pubs.rsc.org
Operation therapy is a common treatment for many cancers, but malignant tumors likely
recur and metastasize after surgery, resulting in treatment failure. In this study, we aimed at …
recur and metastasize after surgery, resulting in treatment failure. In this study, we aimed at …
Chlorogenic acid sustained-release gel for treatment of glioma and hepatocellular carcinoma
H Zhou, D Chen, T Gong, Q He, C Guo, P Zhang… - European Journal of …, 2021 - Elsevier
Chlorogenic acid (CGA) may provide an effective and safe option for tumor treatment.
However, its application is limited because of short residence time in vivo and repeated …
However, its application is limited because of short residence time in vivo and repeated …
Poly (l-glutamic acid)-g-methoxy poly (ethylene glycol)-gemcitabine conjugate improves the anticancer efficacy of gemcitabine
Gemcitabine is widely used for anticancer therapy. However, its short blood circulation time
and poor stability greatly impair its application. To solve this problem, we prepared a poly (l …
and poor stability greatly impair its application. To solve this problem, we prepared a poly (l …
Brain tumor vessels—a barrier for drug delivery
Cancer treatment remains a challenge due to a high level of intra-and intertumoral
heterogeneity and the rapid development of chemoresistance. In the brain, this is further …
heterogeneity and the rapid development of chemoresistance. In the brain, this is further …
Bioscaffold-based study of glioblastoma cell behavior and drug delivery for tumor therapy
K Tran, R Brice, L Yao - Neurochemistry International, 2021 - Elsevier
Glioblastoma multiforme (GBM) is a severe form of brain cancer with an average five-year
survival rate of 6.7%. Current treatment strategies include surgical resection of the tumor …
survival rate of 6.7%. Current treatment strategies include surgical resection of the tumor …
Hydrogel-based drug delivery systems for cancer therapy
Hydrogels have been employed for applications like wounds, burns, dressings, contact
lenses, tissue engineering applications, to name a few. The potential of hydrogel application …
lenses, tissue engineering applications, to name a few. The potential of hydrogel application …
Matrix metalloproteinase responsive hydrogel microplates for programmed killing of invasive tumour cells
Interactive materials are an emerging class of systems that can offer control over response
and adaptivity in polymer structures towards the meso-and macroscale. Here, we use …
and adaptivity in polymer structures towards the meso-and macroscale. Here, we use …
Perspective on Translating Biomaterials Into Glioma Therapy: Lessons From in Vitro Models
RC Cornelison, JM Munson - Frontiers in materials, 2018 - frontiersin.org
Glioblastoma (GBM) is the most common and malignant form of brain cancer. Even with
aggressive standard of care, GBM almost always recurs because its diffuse, infiltrative …
aggressive standard of care, GBM almost always recurs because its diffuse, infiltrative …
Detection of Label-Free Drugs within Brain Tissue Using Orbitrap Secondary Ion Mass Spectrometry as a Complement to Neuro-Oncological Drug Delivery
Historically, pre-clinical neuro-oncological drug delivery studies have exhaustively relied
upon overall animal survival as an exclusive measure of efficacy. However, with no adopted …
upon overall animal survival as an exclusive measure of efficacy. However, with no adopted …
An Extensive Review on Hydrogels in Pharmaceutical Drug Delivery Applications.
S Rajaram, SR Dharmalingam… - International …, 2022 - search.ebscohost.com
In recent years pharmaceutical companies are directing towards designing new
pharmaceutical dosage forms of existing medications. Recent breakthroughs have been the …
pharmaceutical dosage forms of existing medications. Recent breakthroughs have been the …