Polypharmacy in older adults: a narrative review of definitions, epidemiology and consequences

F Pazan, M Wehling - European geriatric medicine, 2021 - Springer
Background The number of older adults has been constantly growing around the globe.
Consequently, multimorbidity and related polypharmacy have become an increasing …

Benzodiazepines in Alzheimer's disease: beneficial or detrimental effects

HM Al-Kuraishy, AI Al-Gareeb, HM Saad… - …, 2023 - Springer
Dementia is considered a clinical syndrome characterized by cognitive dysfunction and
memory loss. Alzheimer's disease (AD) is the most common type of dementia. AD is linked …

Insights on benzodiazepines' potential in Alzheimer's disease

HM Al-Kuraishy, AI Al-Gareeb, AA Alsayegh… - Life Sciences, 2023 - Elsevier
Alzheimer's disease (AD) is the most frequent type of dementia characterized by the
deposition of amyloid beta (Aβ) plaque and tau-neurofibrillary tangles (TNTs) in the brain …

Incidence and risk factors of falls among older people in nursing homes: systematic review and meta-analysis

L Shao, Y Shi, X Xie, Z Wang, ZA Wang… - Journal of the American …, 2023 - Elsevier
Objectives Falls are common among older people in nursing homes, and the assessment of
fall risk factors is critical for the success of fall prevention interventions. This study aimed to …

Prevalence of psychotropic polypharmacy in nursing home residents with dementia: a meta-analysis

DJ Jester, V Molinari, JC Zgibor… - International …, 2021 - cambridge.org
Objectives: Nursing home (NH) residents with dementia is exposed to high rates of
psychotropic prescriptions. Our objectives were to:(1) pool the prevalence estimates of …

Change in gait speed and fall risk among community-dwelling older adults with and without mild cognitive impairment: a retrospective cohort analysis

CE Adam, AL Fitzpatrick, CS Leary, A Hajat, SD Ilango… - BMC geriatrics, 2023 - Springer
Background Although slow gait speed is an established risk factor for falls, few studies have
evaluated change in gait speed as a predictor of falls or considered variability in effects by …

[HTML][HTML] Factors associated with emergency department visits by people with dementia near the end of life: a systematic review

LE Williamson, CJ Evans, RL Cripps, J Leniz… - Journal of the American …, 2021 - Elsevier
Objectives Emergency department (ED) attendance is common among people with
dementia and increases toward the end of life. The aim was to systematically review factors …

Process evaluation for the care homes independent pharmacist prescriber study (CHIPPS)

L Birt, L Dalgarno, DJ Wright, M Alharthi, J Inch… - BMC Health Services …, 2021 - Springer
Background Medicines management in care homes requires significant improvement.
CHIPPS was a cluster randomised controlled trial to determine the effectiveness of …

Stakeholders' views on the use of psychotropic medication in older people: a systematic review

E Bednarczyk, S Cook, R Brauer, S Garfield - Age and Ageing, 2022 - academic.oup.com
Background psychotropic medication use has been shown to increase with age and has
been associated with increased risk of falls, strokes and mortality. Various guidelines …

Prevalence and preventability of adverse medicine events in a Sample of Australian aged-care residents: a secondary analysis of data from the ReMInDAR Trial

LM Kalisch Ellett, G Dorj, AQ Andrade, RL Bilton… - Drug Safety, 2023 - Springer
Background Aged care residents are vulnerable to the harmful effects of medicines;
however, data on the prevalence and preventability of adverse medicine events in aged …