It is well known that vascular factors and specific social determinants of health contribute to
dementia risk and that the prevalence of these risk factors differs according to race and sex …

Importance Modifiable risk factors are hypothesized to account for 30% to 40% of dementia;
yet, few trials have demonstrated that risk-reduction interventions, especially multidomain …

Dementia is forecast to become increasingly prevalent, particularly in low-and middle-
income countries, and is associated with high human and economic costs. Primary …

Background It is unknown whether multidomain interventions, which might preserve late-life
cognition, affect Alzheimer's disease pathology. Previous studies measured cerebrospinal …

Exercise promotes brain health. Human and animal studies have demonstrated acute and
chronic effects of exercise on brain and cognitive function. 1–3 Exercise is not a magic bullet …

Objectives To provide a comprehensive CERT (Consensus on Exercise Reporting
Template)-based description of the resistance exercise program implemented in the …

Introduction Digital health interventions are cost-effective and easily accessible, but there is
currently a lack of effective online options for dementia prevention especially for people at …

Introduction Modifiable risk factors account for a substantial proportion of Alzheimer's
disease (AD) cases and we currently have a discrete AT (N) biomarker profile for AD …

Many risk factors for dementia, identified from observational studies, are potentially
modifiable. This raises the possibility that targeting key modifiable dementia risk factors may …

Introduction Monoclonal antibodies targeting amyloid-β are the first disease-modifying
treatments for Alzheimer disease to have received FDA-approval. There are three different …