NLRP3 inflammasome is a key multiprotein signaling platform that tightly controls
inflammatory responses and coordinates antimicrobial host defenses by activating caspase …

Background General health checks are common elements of health care in some countries.
These aim to detect disease and risk factors for disease with the purpose of reducing …

Aims/hypothesis Metabolomics technologies have identified numerous blood biomarkers for
type 2 diabetes risk in case− control studies of middle-aged and older individuals. We aimed …

It is the position of the Academy of Nutrition and Dietetics that for adults with prediabetes or
type 2 diabetes, medical nutrition therapy (MNT) provided by registered dietitian nutritionists …

Currently, the global prevalence of diabetes is 8.8%. This figure is expected to increase
worldwide, with the largest changes projected to occur in low-and middle-income countries …

Prediabetes can be defined by the presence of impaired fasting glucose (IFG) and/or
impaired glucose tolerance (IGT), or glycated haemoglobin (HbA1c) to identify individuals at …

Background The major efficacy trials on diabetes prevention have used resource-intensive
approaches to identify high-risk individuals and deliver lifestyle interventions. Such …

Lifestyle intervention (LI) can prevent type 2 diabetes, but response to LI varies depending
on risk subphenotypes. We tested whether individuals with prediabetes with low risk (LR) …

Screening for diabetes implies testing for diabetes in individuals without symptoms who are
unaware of their condition. Screening for diabetes will also detect individuals at increased …

Summary Background The NHS Diabetes Prevention Programme (DPP) is the first
nationwide type 2 diabetes prevention programme targeting people with prediabetes. It was …