Multipotent mesenchymal stromal cells (MSC) have been widely explored for cell-based
therapy of immune-mediated, inflammatory, and degenerative diseases, due to their …

Mesenchymal stromal cells (MSCs) are a subset of heterogeneous non-hematopoietic
fibroblast-like cells that can differentiate into cells of multiple lineages, such as …

Mesenchymal stem cells (MSCs) are isolated from multiple biological tissues—adult bone
marrow and adipose tissues and neonatal tissues such as umbilical cord and placenta. In …

Mesenchymal stromal cells (MSCs) are self-renewing, culture-expandable adult stem cells
that have been isolated from a variety of tissues, and possess multipotent differentiation …

Clinical trials using adult stem cells to regenerate damaged heart tissue continue to this
day,, despite ongoing questions of efficacy and a lack of mechanistic understanding of the …

The therapeutic benefits of mesenchymal stromal cell (MSC) transplantation are attributed to
their secreted factors, including extracellular vesicles (EVs) and soluble factors. The …

Ischaemic heart disease is a leading cause of death worldwide. Injury to the heart is
followed by loss of the damaged cardiomyocytes, which are replaced with fibrotic scar …

Background Exosomes are membranous vesicles generated by almost all cells. Recent
studies demonstrated that mesenchymal stem cell–derived exosomes possessed many …

Administration of mesenchymal stem cells (MSCs) to diseased hearts improves cardiac
function and reduces scar. These effects occur via stimulation of endogenous repair …

Cell therapeutics hold tremendous regenerative potential and the therapeutic effect depends
on the effective delivery of cells. However, current cell delivery carriers with unsuitable …