Cancer metastasis is the major cause of cancer morbidity and mortality, and accounts for
about 90% of cancer deaths. Although cancer survival rate has been significantly improved …

Metastasis is the key cause of treatment failure in most oncological patients. The spreading
of cancer cells to distal tissues and organs can be associated with the epithelial-to …

The Snail family transcription factors have been proposed as important mediators of
epithelial–mesenchymal transition because of their role in down-regulation of E-cadherin …

Ultrasound stimulation is a type of mechanical stress, and low-intensity pulsed ultrasound
(LIPUS) devices have been used clinically to promote fracture healing. However, it remains …

Abstract Transient Receptor Potential Melastatin 4 (TRPM4) is a Ca2+‐activated and voltage‐
dependent monovalent cation channel, which depolarizes the plasma cell membrane …

To develop new and effective chemopreventive agents against bone metastasis, we
assessed the effects of muscadine grape skin extract (MSKE), whose main bioactive …

Ovarian cancer (OC) is the second leading cause of gynecological cancer death worldwide.
Although the list of biomarkers is still growing, molecular mechanisms involved in OC …

The prognosis of patients with hepatocellular carcinoma (HCC) may be improved by novel
treatments focusing on the characteristic metabolic changes of this disease. Therefore, we …

Background Prostate cancer is known as the most common malignancy in men. Chitosan
has generated great interest as a useful biopolymer for the encapsulation of small interfering …

Endochondral bone formation is a multistep process during which a cartilage primordium is
replaced by mineralized bone. Several genes involved in cartilage and bone development …