Abstract The American Society of Regional Anesthesia and Pain Medicine (ASRA) 2012
survey of meeting attendees showed that existing ASRA anticoagulation guidelines for …

The vascular endothelium influences not only the three classically interacting components of
hemostasis: the vessel, the blood platelets and the clotting and fibrinolytic systems of …

Interventional spine and pain procedures cover a far broader spectrum than those for
regional anesthesia, reflecting diverse targets and goals. When surveyed, interventional …

Background—Outcomes in patients with mild to moderate renal function (RF) abnormalities
presenting with acute coronary syndromes (ACS) are not well defined. Methods and Results …

Unstable angina accounts for more than 1 million hospital admissions annually1; 6 to 8
percent of patients with this condition have nonfatal myocardial infarction or die within the …

Background—Molecular imaging is a fast emerging technology allowing noninvasive
detection of vascular pathologies. However, imaging modalities offering high resolution …

ContextThe Enhanced Suppression of the Platelet IIb/IIIa Receptor with Integrilin Therapy
(ESPRIT) trial showed the efficacy of adjunctive, double-bolus eptifibatide therapy in …

During the last decade, intensive efforts have been made to evaluate the role of the platelet
glycoprotein (GP) IIb/IIIa complex in platelet-mediated thrombus formation. Significant efforts …

The main function of platelets is to participate in primary hemostasis through four distinct
steps: adhesion, activation, secretion, and aggregation. Unraveling the molecular …

Interactions proposed to mediate platelet adhesion and aggregation during thrombus
formation. Events are depicted from left to right as they may occur in temporal sequence …