Rotavirus vaccines hold promise to decrease the burden of severe diarrhea in the poorest
countries, where 85% of deaths due to rotavirus occur. However, the potency of live oral …

These recommendations represent the first statement by the Advisory Committee on
Immunization Practices (ACIP) on the use of an oral, live rotavirus vaccine licensed by the …

Background Environmental enteropathy (EE) is a subclinical enteric condition found in low-
income countries that is characterized by intestinal inflammation, reduced intestinal …

Rotavirus is the most common cause of severe gastroenteritis in infants and young children
worldwide. Before initiation of the rotavirus vaccination program in the United States in 2006 …

In February 2006, a live, oral, human-bovine reassortant rotavirus vaccine (RotaTeq®) was
licensed for use among US infants. The Advisory Committee on Immunization Practices …

Oral mucosal vaccines have great promise for generating protective immunity against
intestinal infections for the benefit of large numbers of people especially young children …

Background. The impaired immunogenicity of oral poliovirus vaccine (OPV) in low-income
countries has been apparent since the early field trials of this vaccine. Infection with …

After global eradication of polio is achieved, there will be a need for stockpiles of vaccine to
combat potential outbreaks of poliomyelitis caused by (1) unforeseen release of …

Oral vaccines for polio (OPV) and rotavirus are less effective in children in the developing
world. The reasons for this are not well understood. We tested for risk factors for poor …

To estimate long-term poliovaccine virus persistence among immunodeficient patients with
vaccine-associated paralytic poliomyelitis (iVAPP), cases reported in the United States …