Abstract Purpose of Review The developmental origins of health and disease (DOHaD)
hypothesis posits that the perinatal environment can impact fetal and later life health. The …

Preterm birth (PTB) is the leading cause of death in children under five, yet comprehensive
studies are hindered by its multiple complex etiologies. Epidemiological associations …

Background Preterm birth remains a leading obstetrical complication because of the
incomplete understanding of its multifaceted etiology. It is known that immune alterations …

A well-functioning placenta is crucial for normal gestation and regulates the nutrient, gas,
and waste exchanges between the maternal and fetal circulations and is an important …

Background Spontaneous preterm birth accounts for most preterm births and leads to
significant morbidity in the newborn and childhood period. This subtype of preterm birth …

Background: Phthalates are commonly used endocrine-disrupting chemicals that are
ubiquitous in the general population. Prenatal phthalate exposure may alter placental …

The developmental origins and evolutionary histories of cell types, tissues, and organs
contribute to the ways in which their dysfunction produces disease. In mammals, the nature …

Despite the indispensable role of the placenta in the successful course of pregnancy,
regulation of its dynamic transcriptome is still underexplored. The purpose of this literature …

Background: Despite decades of research, the pathogenesis of spontaneous preterm birth
(PTB) remains largely unknown. Limited currently available data on PTB pathogenesis are …

Heat shock proteins are involved in the response to stress including activation of the
immune response. Elevated circulating heat shock proteins are associated with …