Liver insulinization as a driver of triglyceride dysmetabolism

JR Cook, MA Hawkins, UB Pajvani - Nature Metabolism, 2023 - nature.com
Metabolic dysfunction-associated fatty liver disease (MAFLD) is an increasingly prevalent
fellow traveller with the insulin resistance that underlies type 2 diabetes mellitus. However …

Precision nutrition for targeting pathophysiology of cardiometabolic phenotypes

CE Shannon, MB Ní Chathail, SM Mullin… - Reviews in Endocrine …, 2023 - Springer
Obesity is a heterogenous disease accompanied by a broad spectrum of cardiometabolic
risk profiles. Traditional paradigms for dietary weight management do not address biological …

Relationship between serum β-hydroxybutyrate and hepatic fatty acid oxidation in individuals with obesity and NAFLD

MP Moore, G Shryack, I Alessi… - American Journal …, 2024 - journals.physiology.org
Nonalcoholic fatty liver disease (NAFLD) is characterized by excess lipid accumulation that
can progress to inflammation (nonalcoholic steatohepatitis, NASH), and fibrosis. Serum β …

Intratumoral lipdi metabolic reprogramming as a pro-tumoral regulator in the tumor milieu

R Wang, Q Hu, Y Wu, N Guan, X Han… - Biochimica et Biophysica …, 2023 - Elsevier
Reprogramming of the tumor microenvironment (TME) is a hallmark of cancer. Metabolic
reprogramming is a vital approach to sustaining the energy supply in the TME. This …

Bridging Metabolic-Associated Steatotic Liver Disease and Cardiovascular Risk: A Potential Role for Ketogenesis

RS del Villar-Carrero, A Blanco, LD Ruiz… - Biomedicines, 2024 - mdpi.com
The prevalence of cardiovascular diseases (CVDs) is a growing global health concern.
Recent advances have demonstrated significant reductions in acute cardiovascular events …

[HTML][HTML] Fasting-regulated mechanisms in inter-organ crosstalk

AJ Alfaro, S Herzig - Current Opinion in Endocrine and Metabolic Research, 2024 - Elsevier
The adaptation to changing environmental cues represents a key prerequisite for the
survival of an organism. Mammals, including humans, have evolved intricate endocrine …

How To Fatten A Mammal

B Marshall - fireinabottle.net
This video serves as a sort of road map of Fire In A Bottle topics. On the blog and video
series I've drilled into numerous topics and their relationship with obesity: PUFA, MUFA, The …