Plausible PEPPSI catalysts for direct C–H functionalization of five-membered heterocyclic bioactive motifs: synthesis, spectral, X-ray crystallographic characterizations …

D Bensalah, L Mansour, M Sauthier, N Gurbuz… - RSC …, 2023 - pubs.rsc.org
In this study, a series of benzimidazolium salts were synthesized as asymmetric N-
heterocyclic carbene (NHC) precursors. Nine novel palladium complexes with the general …

Benzimidazole-Based NHC Metal Complexes as Anticancer Drug Candidates: Gold (I) vs. Platinum (II)

P Kapitza, P Grabher, A Scherfler, K Wurst, B Kircher… - Inorganics, 2023 - mdpi.com
Herein, we present a comparative study on the chemistry and biological activity of N-
heterocyclic carbene (NHC) Pt (II)/Au (I) complexes. Accordingly, representative compounds …

Therapeutic potential of Ag (i)–, Au (i)–, and Au (iii)–NHC complexes of 3-pyridyl wingtip N-heterocyclic carbenes (NHCs) against lung cancer

PK Behera, L Maity, S Roy, A Das, P Sahu… - New Journal of …, 2023 - pubs.rsc.org
Herein, we report the easy synthetic approaches, structural features, theoretical studies, and
extensive bioactivity of [Ag (1) 2][PF6](2),[Au (1) 2][PF6](3), and [Au (1) Cl3](4) compounds …

Development of Cytotoxic GW7604-Zeise's Salt Conjugates as Multitarget Compounds with Selectivity for Estrogen Receptor-Positive Tumor Cells

P Grabher, P Kapitza, N Hörmann… - Journal of Medicinal …, 2024 - ACS Publications
(E/Z)-3-(4-((E)-1-(4-Hydroxyphenyl)-2-phenylbut-1-enyl) phenyl) acrylic acid (GW7604) as a
carrier was esterified with alkenols of various lengths and coordinated through the ethylene …

Synthesis, characterization and anti-ovarian cancer activities of novel biphenyl-NHC-gold (I) complexes

M Wang, Y Li, G Jiang, F Li, Y Lu, W Liu - Journal of Organometallic …, 2024 - Elsevier
Fifteen novel biphenyl-N-heterocyclic carbene (NHC)-gold (I) complexes were designed and
synthesized to treat ovarian cancer (OC). Among these, complex Au-1 showed significant …

Dibromo-and Dichlorotriphenylphosphino N-Acyclic Carbene Complexes of Platinum (II)—Synthesis and Cytotoxicity

A Farasat, L Labella, ML Di Paolo, L Dalla Via… - Inorganics, 2023 - mdpi.com
Some new dichloro-and dibromotriphenylphosphino isonitrile and N-acyclic (NAC) carbene
complexes of platinum (II) were synthesized, starting from suitable dinuclear precursors. The …