Anaplastic thyroid cancer (ATC) is one of the deadliest human cancers and it is less than 2%
of thyroid carcinomas (TCs). The standard treatment of ATC includes surgical debulking …

Anaplastic thyroid cancer (ATC) is one of the most lethal of all cancers. It is more common in
women and occurs primarily in older patients. ATC has a median overall survival of 3–5 …

Abstract The Japan Associations of Endocrine Surgeons has developed the revised version
of the Clinical Practice Guidelines for Thyroid Tumors. This article describes the guidelines …

Objective To determine the prevalence of mutations in known thyroid oncogenes and
signalling pathways amendable to targeted therapy in a large cohort of ATC. Results In 118 …

Background: Anaplastic thyroid carcinoma (ATC), the most aggressive type of thyroid
cancer, has no effective therapy. Due to its dismal prognosis, it is vital to understand the …

Next-generation sequencing (NGS) in thyroid cancer allows for simultaneous high-
throughput sequencing analysis of variable genetic alterations and provides a …

Well-differentiated thyroid cancer accounts for the majority of endocrine malignancies and,
in general, has an excellent prognosis. In contrast, the less common poorly differentiated …

The current study aims to evaluate for the first time the inhibitory roles of miR-205 in the
pathogenesis of anaplastic thyroid carcinoma. In addition, we investigated the mechanisms …

Anaplastic thyroid cancer (ATC) is one of the most lethal human malignancies that currently
has no effective therapy. We performed quantitative high-throughput screening (qHTS) in …

Purpose The anaplastic thyroid carcinoma (ATC) is the most aggressive thyroid cancer with
a high mortality rate. Since nutraceuticals may exert beneficial effects on tumor biology …